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Significance of Serum Magnesium in Parathyroid Hormone Level in Patients with Chronic Kidney Disease.
Endocr Metab Immune Disord Drug Targets
January 2025
Department of Nephrology, the Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
Introduction: In chronic kidney disease (CKD) patients, elevated parathyroid hormone (PTH) is linked to cardiovascular mortality and morbidity. Levels of PTH are influenced by serum phosphate (P) and calcium (Ca), but little is known about the impact of magnesium (Mg) on PTH. Hence, this study investigated the relationship between PTH and Mg in peritoneal dialysis (PD) patients and non-dialysis patients from three hospitals in China.
View Article and Find Full Text PDFMeasurement of urine calcium, magnesium and phosphate: Preanalytical considerations in the elimination of the acidification step.
Clin Chim Acta
January 2025
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia, PA, United States. Electronic address:
Background: Traditionally, urine analysis of calcium (Ca), magnesium (Mg) and phosphate (Phos) requires acidification of the sample. This study aims to assess the need for acidification and evaluate preanalytical factors that influence the accurate measurement of these analytes in urine.
Results: A total of 107 spot urine samples from patients with a median age of 9 years (95 % ≤ 21 years of age, range 5 days to 46 years) were analyzed for Ca (n = 94), Mg (n = 97), and Phos (n = 102) with and without acidification.
The association between domestic water hardness and kidney stone disease: a prospective cohort study from the UK Biobank.
Int J Surg
December 2024
Department of Urology, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China.
Background: Kidney stone disease is a common surgical disease and significant public health issue, may be influenced by environmental factors such as domestic water hardness and its related minerals. Previous studies have shown inconsistent and controversial results regarding the impact of domestic water hardness on kidney stone formation.
Methods: This prospective cohort study analyzed data from 288,041 participants in the UK Biobank with no prior history of kidney stones from 2006-2024.
The effect of sevelamer on serum calcification propensity in patients with chronic kidney disease: the results of a multicentre, double-blind, placebo-controlled, randomized clinical trial.
Clin Kidney J
January 2025
MP3CV Laboratory, Jules Verne University of Picardie, Amiens, France.
Background: The serum calcification propensity test (or T50 test) might become a standard tool for the assessment of vascular calcification risk and T50 might be a valuable biomarker in clinical trials of treatments intended to slow the progression of vascular calcification. Literature data suggest that non-calcium-containing phosphate binders can influence T50 in chronic dialysed patients. However, it is not clear whether similar interventions are effective in patients at earlier stages of chronic kidney disease (CKD).
View Article and Find Full Text PDFEvaluating the potential of in alleviation of aluminium stress in .
3 Biotech
January 2025
Department of Agronomy, Abdul Wali Khan University, Mardan, 23200 Khyber Pakhtunkhwa Pakistan.
Soil contamination with toxic heavy metals [such as aluminum (Al)] is becoming a serious global problem due to the rapid development of the social economy. Although plant growth-promoting rhizo-bacteria (PGPR) are the major protectants to alleviate metal toxicity, the study of these bacteria to ameliorate the toxic effects of Al is limited. Therefore, the present study was conducted to investigate the combined effects of different levels of (5 ppm and 10 ppm) of accession number of MT123456 on plant growth and biomass, photosynthetic pigments, gas exchange attributes, oxidative stress and response of antioxidant compounds (enzymatic and nonenzymatic), and their specific gene expression, sugars, nutritional status of the plant, organic acid exudation pattern and Al accumulation from the different parts of the plants, which was spiked with different levels of Al [0 µM (i.
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