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Pleural Rosai-Dorfman disease complicated with renal clear cell carcinoma: a case report and literature review.
Front Oncol
January 2025
Department of Radiology, Daping Hospital, Army Medical University, Chongqing, China.
Background: Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare non-malignant disorder characterized by excessive proliferation of histiocytes, the cause of which remains unknown. Although the lymph nodes are the most commonly affected site, some patients may present with extranodal involvement, particularly in the skin, nasal cavity, eyes, and bones. In this report, we aim to present a unique case of RDD with pleural involvement in a 61-year-old patient.
View Article and Find Full Text PDFWhen neck lymph nodes metastases do not origin from a head and neck unknown primary.
Curr Opin Otolaryngol Head Neck Surg
December 2024
Service d'Oto-rhino-laryngologie - Chirurgie cervico-faciale, Centre Hospitalier Universitaire Vaudois (CHUV), Université de Lausanne (UNIL), Lausanne, Switzerland.
Purpose Of Review: The evidence for a standardized approach to the management of cervical metastasis from a distant primary tumour is limited. The objective of this review is to provide an overview of the current status of research in this field and to present the latest diagnostic and therapeutic approaches.
Recent Findings: Although infraclavicular tumours are typically observed to metastasise to levels IV and V of the neck, all levels may potentially be affected.
Ultrahigh piezoelectric performances of (K,Na)NbO based ceramics enabled by structural flexibility and grain orientation.
Nat Commun
January 2025
State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, China.
(K,Na)NbO-based ceramics are deemed among the most promising lead-free piezoelectric materials, though their overall piezoelectric performance still lags behind the mainstream lead-containing counterparts. Here, we achieve an ultrahigh piezoelectric charge coefficient d ∼ 807 pC·N, along with a high longitudinal electromechanical coupling factor (k ∼ 88%) and Curie temperature (T ∼ 245 °C) in the (K,Na)(NbSb)O-BiNaZrO-BiFeO (KNN-xSb) system through structural flexibility and grain orientation strategies. Phenomenological models, phase field simulations and high-angle annular dark-field scanning transmission electron microscopy reveal that the structural flexibility originates from the high Coulomb force between K/Na ions and Sb ions in the KNN-xSb system, while the grain orientation promotes the displacement of B-site cations leveraging the engineered domain configuration.
View Article and Find Full Text PDFViral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution.
PLoS Biol
January 2025
CIRB, CNRS, INSERM, Collège de France, Université PSL, Paris, France.
Human papillomavirus (HPV) infections drive one in 20 new cancer cases, exerting a particularly high burden on women. Most anogenital HPV infections are cleared in less than two years, but the underlying mechanisms that favour persistence in around 10% of women remain largely unknown. Notwithstanding, it is precisely this information that is crucial for improving treatment, screening, and vaccination strategies.
View Article and Find Full Text PDFHigh risk of drug-resistant tuberculosis in IGRA-negative contacts: should preventive treatment be considered?
Infection
January 2025
Department of Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Parkallee 35, Borstel, Germany.
Purpose: Deciding whether to provide preventive treatment to contacts of individuals with multidrug-resistant (MDR) tuberculosis is complex.
Methods: We present the diagnostic pathways, clinical course and outcome of tuberculosis treatment in eight siblings from a single family. Tuberculosis disease was diagnosed by Mycobacterium tuberculosis culture and molecular detection of M.
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