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Little evidence based information exists in the medical literature on the mortality of abusers of anabolic androgenic steroids. These individuals range from competitive athletes and body builders to those whose who use physician prescribed mega-doses. Life insurance medical directors have little guidance on how to underwrite these individuals when presented with their applications.
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Ugeskr Laeger
October 2024
Kardiologisk Afdeling, Københavns Universitetshospital - Herlev og Gentofte Hospital.
Abuse of androgenic anabolic steroids (AAS) is associated with a range of cardiovascular side effects, summarized in this review. Apart from being linked to cardiovascular risk factors such as hypertension and dyslipidaemia, AAS abuse is associated with coronary atherosclerosis and imparts a pro-coagulative state, predisposing to thromboembolic disease. Finally, AAS abuse leads to left ventricular hypertrophy and dysfunction, which can ultimately result in heart failure.
View Article and Find Full Text PDFAdministration Route Differentiation of Altrenogest via the Metabolomic LC-HRMS Analysis of Equine Urine.
Molecules
October 2024
Centre for Forensic Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Altrenogest, also known as allyltrenbolone, is a synthetic form of progesterone used therapeutically to suppress unwanted symptoms of estrus in female horses. Altrenogest affects the system by decreasing levels of endogenous gonadotrophin and luteinizing and follicle-stimulating hormones, which in turn decreases estrogen and mimics the increase of progesterone production. This results in more manageable mares for training and competition alongside male horses while improving the workplace safety of riders and handlers.
View Article and Find Full Text PDFSex differences in elite track and field performances and inferences about steroid doping.
Exp Physiol
November 2024
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Females likely experience larger performance benefits from androgenic-anabolic steroids than males. We set out to determine if there were temporal differences in select athletics (track and field) records between females and males. Exploratory aims included: (1) evaluating the improvements in female and male world records over time, and (2) investigating the influence of doping programs on male and female world records before and after 1990, when sports governing bodies began to implement random out-of-competition and systematic in-competition drug testing.
View Article and Find Full Text PDFResponse to Dr. Akin Torun's letter on androgenic-anabolic steroid use and carotid ıntima-media thickness.
J Sports Med Phys Fitness
December 2024
Division of Endocrinology and Metabolism, Toros State Hospital, Mersin, Türkiye -
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