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Purpose: There are authentic observations of combination of systemic lupus erythematosus (SLE) with systemic sclerosis (SS) and with polymyositis defined as overlap syndromes. The prevalence of pulmonary hypertension is unknown in SS-SLE overlap syndrome because of its rarity. The aim of our study was to precise clinical, paraclinical and evolutive features of pulmonary hypertension in patients with systemic sclerosis-systemic lupus erythematosus (SS-SLE) overlap syndrome.

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Acute hypokalemic paralysis is a rare and potentially fatal condition, with few related causes, one of which highlights distal renal tubular acidosis (dRTA). Distal renal tubular acidosis is a rare complication of several autoimmune diseases such as systemic lupus erythematosus, Sjögren's syndrome, and Hashimoto thyroiditis. We report a case of a lupic patient who presented rapidly progressive quadriparesis in the context of active renal disease.

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[Hypereosinophilic syndrome as paraneoplastic presentation in an adolescent].

Rev Alerg Mex

July 2014

Servicio de Alergia e Inmunología Clínica, Unidad Médica de Alta Especialidad, Hospital de Especialidades Antonio Fraga Mouret, Centro Médico Nacional La Raza, Instituto Mexicano de Seguro Social, México, DF.

Article Synopsis
  • Hypereosinophilic syndrome (HS) involves high eosinophil counts and organ damage, diagnosed after excluding other causes, and can present uniquely, as in a case of a 13-year-old girl previously treated for B cell lymphoblastic leukemia.
  • After two years in remission, she developed various symptoms like rash, hair loss, and respiratory issues, but early tests indicated only hypereosinophilia and no cancerous cells.
  • Despite treatment and investigations revealing complications like eosinophilic pneumonitis and leucocytoclastic vasculitis, her condition deteriorated, leading to a reemergence of leukemia, and unfortunately, she passed away.
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Acquired inhibitors of coagulation causing bleeding manifestations are rare in children. They emerge, normally in the context of autoimmune diseases or drug ingestion, but transient and self-limiting cases can occur after viral infection. We describe, an otherwise healthy, 7-year-old girl who had gingival bleeding after a tooth extraction.

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Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to a drug exposure. We report a 34-year-old woman with multiple sclerosis who developed, while being treated with interferon β-1a, myalgia and associated with wrist synovitis. Clinical and immunologic investigations were in favor of systemic lupus erythematosus.

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