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Klinefelter syndrome and mediastinal germ cell tumors.
Am J Med Genet A
March 2006
Hospital for Children and Adolescents, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.
Unlabelled: Precocious puberty is not a typical manifestation of patients with Klinefelter syndrome (KS). However, there is an increased incidence of mediastinal germ cell tumors (M-GCT) in KS, whereas the discussion of a generally higher tumor risk in this condition is still controversial. A rare subgroup of KS patients consists of prepubertal children with precocious puberty due to human chorionic gonadotropin (hCG)-producing M-GCTs.
View Article and Find Full Text PDFAcute phase proteins in "small for dates" babies. II. Haptoglobin, transferrin, alpha-1-feto protein, alpha-1-acid glycoprotein and caeruloplasmin levels.
Afr J Med Med Sci
October 1992
Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria.
Haptoglobin, transferrin, alpha-1-feto-protein (AFP), alpha-1-acid glycoprotein (AAGP) and caeruloplasmin levels were estimated in 14 "small for dates" (SFD) and 31 "appropriate for dates" (AFD) babies by the single radial immunodiffusion method. The mean caeruloplasmin levels was observed to be significantly reduced in the SFD babies when compared with the AFD babies (t = 3.4582, P < 0.
View Article and Find Full Text PDF[Serum alpha 1-fetoprotein and extrahepatic digestive cancers. Apropos of 4 further cases].
J Chir (Paris)
November 1978
The authors report four new cases of primary digestive carcinoma other than hepatoma with alpha 1 feto-protein in the serum (greater than 200 ng/ml). Two were carcinoma of the colon without liver metastases. The remaining two were also colonic carcinoma but with liver metastases.
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