AI Article Synopsis

  • Lactic dehydrogenase and beta-glucuronidase levels were measured in tissue culture fluids and cellular lysates from two specific cell lines infected with rabies virus.
  • In the infected cultures, an increase in lysosomal enzyme activity was observed starting from day 4 of the infection.
  • Interestingly, this increase in enzyme activity occurred without any signs of cell damage (cytopathic effect) during the observation period.

Article Abstract

Lactic dehydrogenase and beta-glucuronidase were assayed in tissue culture fluids and cellular lysates, respectively, from BHK-21/13S and Iota cell cultures infected with rabies virus. Activation of lysosomal enzymes was shown from the day 4 of infection on, without any indication of cytopathic effect.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC416350PMC
http://dx.doi.org/10.1128/iai.4.5.546-549.1971DOI Listing

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