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Biomechanical Principles of Spinal Deformity Correction in the Thoracolumbar Spine.
J Am Acad Orthop Surg
January 2025
From the Children's Mercy Hospital, Kansas City, MO (Shaw), Children's Health Ireland at Temple Street, Dublin, Ireland (O'Sullivan), the Department of Mechanical Engineering, Polytechnique Montreal, Montreal, Quebec, Canada (Wang and Aubin), and the Sainte-Justine University Hospital Center, Montreal, Quebec, Canada (Wang and Aubin).
Thoracolumbar spinal deformities are a pervasive condition affecting the adolescent and adult patient population. These deformities represent three-dimensional alterations in the coronal, sagittal, and transverse planes with implication on the local, regional, and global alignment. With continued studies, the importance of the overall correction on long-term outcomes has been established.
View Article and Find Full Text PDFUse of Preoperative Spinal Angiography in Severe Spinal Deformity Patients Who Require Thoracic 3 Column Osteotomy: A Case Series and Review of the Literature.
Oper Neurosurg (Hagerstown)
January 2025
Department of Neurosurgery, NYU Langone Health, New York, New York, USA.
Background And Objectives: Three-column osteotomy (3CO) offers substantial spinal deformity correction. Thoracic neurovascular bundle sacrifice is often required, and anterior spinal artery (ASA) perfusion can be compromised. Spinal angiography allows localization of variable ASA vascular contribution.
View Article and Find Full Text PDFCharacteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report.
Heliyon
January 2025
Guangdong Provincial Biotechnology Research Institute (Guangdong Provincial Laboratory Animals Monitoring Center), Guangzhou, Guangdong, 510663, China.
Spondyloarthritis is a prevalent and persistent condition that significantly impacts the quality of life. Its intricate pathological mechanisms have led to a scarcity of animal models capable of replicating the disease progression in humans, making it a prominent area of research interest in the field. To delve into the pathological and physiological traits of spontaneous non-human primate spondyloarthritis, this study meticulously examined the disease features of this natural disease model through an array of techniques including X-ray imaging, MRI imaging, blood biochemistry, markers of bone metabolism, transcriptomics, proteomics, and metabolomics.
View Article and Find Full Text PDFMotor neuron diseases are not exclusively motor; the SSR paradigm.
Amyotroph Lateral Scler Frontotemporal Degener
January 2025
2nd Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece.
Motor Neuron Diseases (MNDs), familial and sporadic, are progressive neurodegenerative disorders that, for an extended period in the past, were considered purely motor disorders. During the course of the disease, however, some patients exhibit concomitant non-motor signs; thus, MNDs are currently perceived as multisystem disorders. Assessment of non-motor symptoms is usually performed clinically, although laboratory tests can also be routinely used to objectively evaluate these symptoms.
View Article and Find Full Text PDFDiagnosis, Classifications and Treatment of Os Odontoideum: WFNS Spine Committee Recommendations.
Spine (Phila Pa 1976)
January 2025
Department of Neurosurgery, Lilavati Hospital and Research Center, Bandra, Mumbai, India.
Study Design: A systematic literature review and consensus using Delphi method.
Objective: The aim was to formulate consensus recommendations regarding the natural history, diagnosis, classification and optimal treatment of Os Odontoideum with global applicability.
Summary Of Background: Os odontoideum (OO) is a rare anomaly of the cranio-vertebral junction (CVJ).
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