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[Prescription of diphosphonates in ambulatory oncology. A study of the health insurance medical services].

Presse Med

November 1996

Service Médical, Caisse Nationale d'Assurance-Maladie des Professions Indépendantes (CANAM), Saint-Denis.

Objectives: As requested by the Health Ministry, the Agricultural (Mutualité Sociale Agricole) and Independant Professions (Assurance Maladie des Professions Indépendantes) Health Insurances carried out a survey to analyse the use of second generation oral biphosphonates.

Methods: The data, from 3,414 prescriptions, gathered over the twelve months from May '93, showed that clodronate is prescribed mainly for breast cancer (35%), prostate cancer (23%), multiple myeloma (19%) and carcinoma of the lung (7%). The other prescriptions (16%) were either related to various malignant diseases (18 types encountered) or non-malignant diseases (mainly osteoporosis, but also Paget's disease of bone and hyperparathyroidism).

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[Diffuse osteo-condensing myeloma with thyroid localization].

Rev Rhum Mal Osteoartic

December 1989

Service de Médecine Interne et Rhumatologie, CHU Côte de Nacre, Caen.

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A case of IgG myeloma with eburnation of the femoral and ileoischiopubic bones is described. A review of the literature confirmed the rarity of osteosclerotic myeloma, especially if other possible causes of bone eburnation or the typical contemporary existence of osteolysis are excluded. The hypothesis that osteosclerotic myeloma may constitute an autonomous form of the disease, probably related to the type and/or extent of the proliferating bone is discussed.

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