Within the set of 200 strains of E. coli isolated from healthy calves and 60 strains of E. coli isolated from calves suffering from diarrhoea we compared the incidence and transfer of determinants of antibioticoresistance, colicinogenesis and hemolytical activity. A significant difference in the incidence and independent mobility of the agents under examination in favour of E. coli from calves suffering from diarrhoea was determined in the case of resistance to chloramphenicol. The increased incidence and independent mobility of the chloramphenicol element in the antibioticoresistent strains of E. coli isolated from calves suffering from diarrhoea can be explained by the three to five-day therapy with a chloramphenicol product.

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