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Efficacy and safety of Anlotinib in combination with gemcitabine and cisplatin as a first-line treatment for recurrent or metastatic nasopharyngeal carcinoma: A single-arm clinical trial.
Int J Cancer
January 2025
Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China.
The effectiveness and safety of combining anlotinib with gemcitabine and cisplatin in the first-line treatment of recurrent/metastatic nasopharyngeal carcinoma (R/M NPC) have not been definitively established. This research seeks to investigate the potential benefits and risks of utilizing this combination therapy in the first-line management of R/M NPC. The research involved 22 individuals diagnosed with R/M NPC and who had not undergone any previous treatment.
View Article and Find Full Text PDFEvaluation of macular retinal oximetry across different levels of diabetic retinopathy: a cross sectional study.
BMC Ophthalmol
January 2025
College of Optometry, University of Houston College of Optometry, 4401 Martin Luther King Blvd, 77204-2020, Houston, TX, USA.
Background: This study evaluates retinal oxygen saturation and vessel density within the macula and correlates these measures in controls and subjects with type 2 diabetes (DM) with (DMR) and without (DMnR) retinopathy. Changes in retinal oxygen saturation have not been evaluated regionally in diabetic patients.
Methods: Data from seventy subjects (28 controls, 26 DMnR, and 16 DMR were analyzed.
Frustration Intolerance Scale for Students.
Clin Psychol Psychother
January 2025
Department of Psychology, University of Oradea, Oradea, Romania.
Background: Frustration intolerance (FI) is the belief that reality should meet our desires for ease, pleasure and comfort. Although extensively studied in adults, tools for measuring FI in children and adolescents are scarce. The Frustration Intolerance Scale for Students (FISS) was developed to fill this gap.
View Article and Find Full Text PDFPsychological burden and its correlates in patients with chronic plaque psoriasis attending three tertiary care centers in Sri Lanka.
Arch Dermatol Res
January 2025
Faculty of Medicine, University of Ruhuna, Matara, Sri Lanka.
Psoriasis is associated with psychological distress among the affected due to unsightly skin lesions, chronicity and the cultural and social stigma linked with the disease. The pathophysiological link between psoriasis and depression creates a vicious cycle in the skin and brain axis. This study evaluates the psychological comorbidity of patients with chronic plaque psoriasis (CPP).
View Article and Find Full Text PDFIs routine hearing screening necessary in patients with inflammatory bowel disease - a prospective study.
Eur Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.
Purpose: To compare audiological profiling and association of hearing loss in different types of IBD and evaluate the degree of hearing impairment based on duration of illness and age parameters.
Methods: 120 subjects evaluated at a tertiary centre were divided into 2 groups- Controls and Cases. Cases were sub grouped into Ulcerative colitis (UC) and Crohn's disease based on biopsy.
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