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Intelligent skin disease prediction system using transfer learning and explainable artificial intelligence.
Sci Rep
January 2025
Research Innovation and Entrepreneurship Unit, University of Buraimi, 512, Buraimi, Oman.
Skin diseases impact millions of people around the world and pose a severe risk to public health. These diseases have a wide range of effects on the skin's structure, functionality, and appearance. Identifying and predicting skin diseases are laborious processes that require a complete physical examination, a review of the patient's medical history, and proper laboratory diagnostic testing.
View Article and Find Full Text PDFNeonatal varicella: updates on post-exposure prophylaxis options.
Arch Dis Child
December 2024
Immunization and Vaccine Preventable Diseases, UK Health Security Agency, London, UK.
Extraction and Purification of Flavonoids and Antiviral and Antioxidant Activities of L.
Molecules
December 2024
College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.
The aim of the present study was to optimize the process parameters for the extraction and purification of total flavonoids from L., in addition to analyzing their chemical composition and evaluating their activity against varicella-zoster virus (VZV) and antioxidant activity. The optimum extraction process was determined using one-way and response surface methods with the following conditions: ethanol concentration of 82.
View Article and Find Full Text PDFBugs take the sting out.
Cell Host Microbe
January 2025
Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:
Jiang et al. investigate the role of the microbiota in postherpetic neuralgia (PHN), a chronic pain condition resulting from varicella-zoster virus reactivation. They identify microbiome alterations in PHN patients, linking microbes and pain sensitivity.
View Article and Find Full Text PDFReconstruction of trunk debridement after necrotizing fasciitis complicating varicella lesions with NovoSorb biodegradable temporizing matrix and skin graft: A pediatric case report.
Ann Chir Plast Esthet
January 2025
Department of Plastic and Burns Pediatric Surgery, Hôpital Armand-Trousseau, AP-HP, 26, avenue du Dr-Arnold-Netter, 75012 Paris, France.
This clinical case report describes the reconstructive management of a child who developed a rare aggressive soft tissue infection - necrotizing fasciitis - complicating varicella skin lesions, with a synthetic dermal regenerative template - NovoSorb Biodegradable Temporizing Matrix - in conjunction with a split thickness meshed skin graft. The scarcity of this clinical case, the need to cover large skin defect promptly while facing infectious and pediatric challenges make it interesting to describe NovoSorb Biodegradable Temporizing Matrix in addition to split thickness meshed skin graft a novel treatment in necrotizing fasciitis of the child. A rapid surgical treatment followed by this reconstructive strategy achieved an acceptable functional and aesthetic result, with timely healing despite the severity and extensive surface area of the infection.
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