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First Reported Case of Breast Sporotrichosis in Bahrain.
Cureus
November 2024
Surgery, Arabian Gulf University, Manama, BHR.
Granulomatous mastitis is a chronic inflammation of the breast, mostly of unknown etiology. The treatment would be definitive if the causative organism were isolated. It is characterized histologically by granulomas, formed mostly by polymorph nuclear neutrophils and central necrosis.
View Article and Find Full Text PDFDevelopment and evaluation of a rapid diagnostic method for Sporothrix globosa in Asia using quantitative real-time PCR.
BMC Infect Dis
August 2024
Hospital for Skin Diseases, Shandong First Medical University, Jinan, Shandong, China.
Article Synopsis
- Sporotrichosis is a chronic fungal infection that affects the skin and can spread through the body's lymphatic system, with increasing prevalence and challenging treatment due to a lack of standardized diagnostics and antifungal options.!
- A new quantitative real-time PCR assay was developed to quickly diagnose sporotrichosis and identify specific species, utilizing gene sequence variations in calmodulin and internal transcribed spacer regions.!
- The assay demonstrated 100% sensitivity and specificity, accurately diagnosing S. globosa in clinical specimens, making it a valuable tool for timely and accurate diagnoses of sporotrichosis in patients.!
A diverse spectrum of mycoses histologically diagnosed in Ghana: Insights from a 10-year retrospective study.
Med Mycol
March 2024
Division of Evolution, Infection and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9NT, UK.
In Ghana, most laboratory diagnoses of severe mycoses are based on histopathology findings due to inadequate availability of serology, culture, and molecular tests. The aim of this study was to evaluate the spectrum of mycoses diagnosed in Ghana. We retrospectively reviewed reports from 2012 to 2021 from three major pathology laboratories in Ghana to identify reports indicating the presence of fungal elements and diagnosis of a mycosis, then extracted demographic, clinical history, site of infection, stain(s), used and diagnosed mycosis details.
View Article and Find Full Text PDFA Case of Disseminated Cutaneous Sporotrichosis Mimicking Sarcoidosis, that Required Four Biopsies to Diagnose.
Tokai J Exp Clin Med
April 2023
Department of Dermatology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
A 69-year-old Japanese woman visited Tokai University Oiso hospital with cutaneous ulcers on her left upper arm that appeared in January 2013, and on her right nose that appeared in December of 2013. Neither the two biopsies and tissue culture from the arm lesion nor the biopsy and tissue culture from the nose lesion detected any organism. In December of 2013, she was diagnosed as cutaneous sarcoidosis at Oiso hospital and treated with oral prednisolone for six months, however, did not show improvement.
View Article and Find Full Text PDFLeukocytoclastic Vasculitis Caused by Disseminated Cutaneous Sporotrichosis: A Case Report and Review of the Literature.
Am J Dermatopathol
March 2022
Department of Dermatology, First Hospital of Jilin University, Changchun, P.R. China.
Cutaneous leukocytoclastic vasculitis (CLV) is a vasculitis that involves mainly small blood vessels in the skin. CLV has different causes (drugs, infections, or neoplastic or systemic inflammatory diseases). Sporotrichosis has rarely been associated with CLV.
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