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An optimal method for quantifying the facial sebum level and characterizing facial sebum features.
Skin Res Technol
September 2023
Department of Skin and Cosmetic Research, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Evidence suggests that sebum content is important in skin disorders such as acne. However, sebum levels change depending on the external environment, and quantifying skin sebum levels is challenging. Here, we propose an optimal method for quantifying the facial sebum level.
View Article and Find Full Text PDFCorrelating the Gut Microbiota and Circulating Hormones with Acne Lesion Counts and Skin Biophysical Features.
Microorganisms
August 2023
Integrative Skin Science and Research, Sacramento, CA 95815, USA.
Acne vulgaris is a common inflammatory condition that is multi-factorial and impacted by both intrinsic and extrinsic features. Several previous studies have assessed for correlations between factors such as circulating hormones, stress, or the microbiome. However, there have not been any correlations specifically against lesion counts or differentiating correlations between inflammatory and non-inflammatory lesion counts.
View Article and Find Full Text PDFRandomized Double-Blind Placebo-Controlled Supplementation with Standardized Fruit Extracts Reduces Facial Sebum Excretion, Erythema, and Wrinkle Severity.
J Clin Med
February 2023
Integrative Skin Science and Research, Sacramento, CA 95815, USA.
(TC) is a medicinal plant that exhibits antioxidant, anti-inflammatory, and antibacterial properties and that is widely used in Ayurveda and herbal formulations. However, the skin effects of TC as an oral supplement have not been studied. The objective of this study is to determine if oral TC fruit extract supplementation can modulate the skin's sebum production and reduce the appearance of wrinkles.
View Article and Find Full Text PDFProspective Evaluation of a Topical Botanical Skin Care Regimen on Mild to Moderate Facial and Truncal Acne and Mood.
J Clin Med
February 2023
Integrative Skin Science and Research, Sacramento, CA 95815, USA.
Acne vulgaris is a common inflammatory condition that can be associated with profound psychosocial impacts. Conventional treatment includes topical retinoids, benzoyl peroxide, and antimicrobials, and some may cause irritation and skin dryness. In this 8-week open-label study, we examined the effects of a botanical skin care regimen (Codex Labs Shaant Balancing regimen) on mild to moderate facial and truncal acne.
View Article and Find Full Text PDFProspective Placebo-Controlled Assessment of Spore-Based Probiotic Supplementation on Sebum Production, Skin Barrier Function, and Acne.
J Clin Med
January 2023
Department of Dermatology, University of California-Davis, Sacramento, CA 95816, USA.
Probiotic supplementation has been shown to modulate the gut-skin axis. The goal of this study was to investigate whether oral spore-based probiotic ingestion modulates the gut microbiome, plasma short-chain fatty acids (SCFAs), and skin biophysical properties. This was a single-blinded, 8-week study (NCT03605108) in which 25 participants, 7 with noncystic acne, were assigned to take placebo capsules for the first 4 weeks, followed by 4 weeks of probiotic supplementation.
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