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Individualized positive end-expiratory pressure in laparoscopic surgery: a randomized controlled trial.
Minerva Anestesiol
November 2024
Department of Anesthesiology and Critical Care Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China -
Article Synopsis
- The study investigates how individualized positive end-expiratory pressure (PEEP), based on driving pressure, impacts lung function after laparoscopic colorectal surgery.
- A total of 91 patients were randomly assigned to receive either individualized PEEP or a fixed PEEP, with the main focus being on postoperative functional residual capacity (FRC) and other pulmonary outcomes.
- Results showed that individualized PEEP significantly increased postoperative FRC and improved other measures of lung function compared to the fixed PEEP group, indicating its effectiveness in enhancing ventilation and oxygenation.
Ultra-fast-track cardiac anesthesia in minimally invasive cardiac surgery: a retrospective observational study.
Cardiovasc Diagn Ther
October 2024
Rehabilitation Medicine Center, Department of Anesthesiology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Background: There is no uniformity on the safety profile of ultra-fast-track cardiac anesthesia (UFTCA), and there is a lack of research on the postoperative lung function status of patients with UFTCA. This retrospective study was to examine the benefits of UFTCA on the postoperative recovery and pulmonary function of patients undergoing minimally invasive cardiac surgery (MICS).
Methods: This retrospective study was performed on patients who underwent MICS at Zhejiang Provincial People's Hospital between January 2022 and July 2023.
Hyperoxia-Induced Secondary Respiratory Failure in a Systemic Ischaemia-Reperfusion Injury.
Adv Exp Med Biol
October 2024
Kindai University Faculty of Medicine, Osaka, Japan.
Article Synopsis
- - Recent studies show that breathing pure oxygen (100% O) after cardiac arrest can harm organ function, highlighting the need for careful monitoring of oxygen levels to avoid injury.
- - In a study on rats, those given 100% O showed higher lung injury (measured by wet-to-dry weight ratio) and significant differences in blood gas parameters compared to those given 30% O and healthy controls.
- - The alveolar-arterial oxygen difference (AaDO) strongly correlated with lung injury, suggesting AaDO could serve as a valuable, non-invasive tool for assessing hyperoxic damage in post-cardiac arrest situations.
Control of hyperpnoea and pulmonary gas exchange during prolonged exercise: The role of group III/IV muscle afferent feedback.
J Physiol
October 2024
Department of Anesthesiology, University of Utah, Salt Lake City, UT, USA.
It remains unclear whether feedback from group III/IV muscle afferents is of continuous significance for regulating the pulmonary response during prolonged (>5 min), steady-state exercise. To elucidate the influence of these sensory neurons on hyperpnoea, gas exchange efficiency, arterial oxygenation and acid-base balance during prolonged locomotor exercise, 13 healthy participants (4 females; 21 (3) years, : 46 (8) ml/kg/min) performed consecutive constant-load cycling bouts at ∼50% (20 min), ∼75% (20 min) and ∼100% (5 min) of with intact (CTRL) and pharmacologically attenuated (lumbar intrathecal fentanyl; FENT) group III/IV muscle afferent feedback from the legs. Pulmonary responses were continuously recorded and arterial blood (radial catheter) periodically collected throughout the exercise.
View Article and Find Full Text PDFImpact of staged goal-directed fluid therapy on postoperative pulmonary complications in patients undergoing McKeown esophagectomy: a randomized controlled trial.
BMC Anesthesiol
September 2024
Graduate School of Bengbu Medical College, Bengbu, Anhui, 233004, People's Republic of China.
Background: Our aim was to evaluate the influence of staged goal directed therapy (GDT) on postoperative pulmonary complications (PPCs), intraoperative hemodynamics and oxygenation in patients undergoing Mckeown esophagectomy.
Methods: Patients were randomly divided into three groups, staged GDT group (group A, n = 56): stroke volume variation (SVV) was set at 8-10% during the one lung ventilation (OLV) stage and 8-12% during the two lung ventilation (TLV) stage, GDT group (group B, n = 56): received GDT with a target SVV of 8-12% During the entire surgical procedure, and control group (group C, n = 56): conventional fluid therapy was administered by mean arterial pressure (MAP), central venous pressure (CVP), and urine volume. The primary outcome was the incidence of postoperative pulmonary complications within Postoperative days (POD) 7.
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