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Transforming growth factor β1 genotypes in relation to TGFβ1, interleukin-8, and tumor necrosis factor alpha in induced sputum and blood in cystic fibrosis.
Mediators Inflamm
February 2014
Department of Pediatric Pulmonary, Goethe University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Background: High-producer TGFβ1 genotypes are associated with severe lung disease in cystic fibrosis (CF), but studies combining IL-8, TNFα-, and TGFβ1(+genotype) levels and their impact on CF lung disease are scarce.
Aim: Assessing the relationship between TGF β 1, IL-8, and TNF- α and lung disease in CF in an exacerbation-free interval.
Methods: Twenty four patients delta F508 homozygous (median age 20.
Loss of transforming growth factor beta 1 receptors and its effects on the growth of EBV-transformed human B cells.
J Immunol
August 1991
Department of Pathology, Roger Williams Medical Center-Brown University, Providence, RI 02908.
Transforming growth factor-beta (TGF-beta) is a potent negative regulator of normal human B cell growth mediated by exogenous signals, including IL-2 and low m.w. B cell growth factor 12 kDa (BCGF-12 kDa).
View Article and Find Full Text PDF[Immunological analysis of hydatidiform mole and invasive mole (author's transl)].
Nihon Sanka Fujinka Gakkai Zasshi
June 1980
Thirty-two cases of hydatidiform mole without endometrial invasion of chorial tissue and 17 of invasive mole were studied to ascertain whether these two diseases can be differentiated by various immune parameters. All of hydatidiform 11 of invasive mole were sampled at a state of "mole in utero" (pre-evacuation), but 6 of invasive mole were at a post-evacuation state, respectively. The results were summarized in the following items; 1.
View Article and Find Full Text PDFSerum protein alterations in chickens contact-exposed to Marek's Disease Virus (MDV) were studied by crossed immunoelectrophoresis. Total protein values of infected chickens were initially, i.e.
View Article and Find Full Text PDF26 unequally old groups of blood stains up to 180 days old were examined for the presence of albumin, Ig A, Ig G immunoglobulins, beta 1 C globulin and transferrin. To ensure different external conditions, each group was composed so as to contain blood stains of the same age but preserved under different conditions and on different types of underlying material. Albumin and Ig G immunoglobulin proved to be among the most stable ones.
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