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Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina.
J Neuroinflammation
January 2025
Stark Neurosciences Research Institute, Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Over recent years, the retina has been increasingly investigated as a potential biomarker for dementia. A number of studies have looked at the effect of Alzheimer's disease (AD) pathology on the retina and the associations of AD with visual deficits. However, while OCT-A has been explored as a biomarker of cerebral small vessel disease (cSVD), studies identifying the specific retinal changes and mechanisms associated with cSVD are lacking.
View Article and Find Full Text PDFCase Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus.
Front Pediatr
January 2025
Children's Hospital, Fudan University, Shanghai, China.
Congenital diarrhea and enteropathies (CODEs) are a rare heterogeneous group of inherited disorders that typically present with severe chronic diarrhea during the first weeks of life. As a broad range of illnesses can present similarly in infants, establishing a definitive cause for CODEs is challenging. In this report, two infants were suspected to have CODE, with neonatal-onset chronic diarrhea and protein-losing enteropathy finally found to be due to intestinal malrotation and chronic midgut volvulus.
View Article and Find Full Text PDFThe effect of Tai Chi on plasma homocysteine in 1176 adults: a propensity score matching-based study.
BMC Cardiovasc Disord
January 2025
Department of Cardiac Rehabilitation, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450000, China.
Background: Tai Chi is a low-impact form of exercise that involves a series of slow movements that flow together. Increased plasma homocysteine(Hcy) levels are associated with an increased risk of cardiovascular diseases and may be reduced by exercise. This study aimed to compare plasma Hcy levels and the risk of hyperhomocysteinemia in 1,176 adults with and without Tai Chi exercises.
View Article and Find Full Text PDFGenetic Mediators of Celiac Disease and Premature Ovarian Failure: Hypothyroidism and Systemic Lupus Erythematosus.
Am J Reprod Immunol
February 2025
Department of Gynecology and Obstetrics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Observational studies suggested celiac disease (CD) possibly be a risk factor for premature ovarian failure (POF). However, causality remains unclear. And hypothyroidism and systemic lupus erythematosus may be the mediating factors.
View Article and Find Full Text PDFTelemedicine in Coeliac Disease: In-Person Appointments Are Favoured by Patients With a Lower Education Attainment and Lower Household Income.
J Hum Nutr Diet
February 2025
School of Life and Health Sciences, University of Roehampton, London, UK.
Introduction: A gluten-free (GF) diet, the only treatment for people living with coeliac disease (CD), is challenging, and international guidelines highlight the valuable role of healthcare professionals in enabling self-management. The study aimed to explore the acceptability of telephone and online video consultations for adults with CD.
Methods: A cross-sectional study consisting of an online and paper survey was promoted to adults with CD.
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