In a wild-type strain of Clostridium acetobutylicum isolated from soil, solvent production appeared limited by butanol toxicity. Butanol-resistant mutants have been obtained which produced significantly higher solvent concentrations (about 30%) than the wild-type strain. Some other physiological differences were observed between a selected resistant mutant and the wild-type strain at the level of solvent resistance and sporulation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC238732 | PMC |
| http://dx.doi.org/10.1128/aem.50.5.1238-1243.1985 | DOI Listing |
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