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Electromyography as an Objective Outcome Measure for the Therapeutic Effect of Biofeedback Training to Reduce Post-Paralytic Facial Synkinesis.
Healthcare (Basel)
March 2025
Department of Otorhinolaryngology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.
Biofeedback rehabilitation for facial palsy is not yet routinely available for patients. : To improve evidence, the effect of an intensive two-week facial training combining electromyography (EMG) and visual biofeedback training of 30 patients (76.7% female; median age: 48.
View Article and Find Full Text PDFExamining the role of novelty detection in 20- and 40-Hz auditory steady-state responses.
Neuroimage
March 2025
Department of Psychiatry, Gifu University Graduate School of Medicine, Gifu, Japan.
An auditory steady-state response (ASSR) is an electrophysiological response to periodic stimuli that reflects the synchronization of endogenous oscillations. The 40-Hz ASSR is reduced in patients with schizophrenia, bipolar disorder, and autism spectrum disorder, making it a candidate biomarker for these psychiatric disorders. Previous studies have revealed that experimental conditions such as stimulus duration and inter-stimulus interval tend to affect ASSR, suggesting that novelty detection may play an important role in determining the magnitude of ASSR.
View Article and Find Full Text PDFAmniotic membrane hydrogel as novel injectable platform in combination with metformin for treatment of sciatic nerve injury.
J Appl Biomater Funct Mater
March 2025
Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Peripheral nerve tissue engineering is a field that uses cells, growth factors and biological scaffold material to provide a nutritional and physical support in the repair of nerve injuries. The specific properties of injectable human amniotic membrane-derived hydrogel including growth factors as well as anti-inflammatory and neuroprotective agents make it an ideal tool for nerve tissue repair, and metformin may also aid in nerve regeneration. The aim of this study was to investigate the effects of hydrogel derived from amniotic membrane (AM) along with metformin (MET) administration in the repair of sciatic nerve injury in male rats.
View Article and Find Full Text PDFFam163a knockdown and mitochondrial stress in the arcuate nucleus of hypothalamus reduce AgRP neuron activity and differentially regulate mitochondrial dynamics in mice.
Acta Physiol (Oxf)
April 2025
Department of Physiology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.
Aim: Mitochondria play key roles in neuronal activity, particularly in modulating agouti-related protein (AgRP) and proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC), which regulates food intake. FAM163A, a newly identified protein, is suggested to be part of the mitochondrial proteome, though its functions remain largely unknown. This study aimed to investigate the effects of Fam163a knockdown and mitochondrial dysfunction on food intake, AgRP neuron activity, and mitochondrial function in the hypothalamus.
View Article and Find Full Text PDFManual therapy compared to surgery in the treatment of moderate carpal tunnel syndrome.
Postep Psychiatr Neurol
December 2024
Department of Neurology, Medical University of Bialystok, Bialystok, Poland.
Purpose: The objective of this study was to assess the efficacy of manual therapy, specifically using the Maitland concept, in treating carpal tunnel syndrome (CTS), and to compare its effectiveness with surgical decompression of the median nerve.
Methods: A total of 69 patients were enrolled and divided into two groups: a control group (undergoing surgery) and treatment group (receiving manual therapy). Subgroups were formed based on gender, considering factors such as grip strength.
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