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Psychiatric, Neurological, and Somatic Comorbidities in Intermittent Explosive Disorder.

JAMA Psychiatry

January 2025

Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, SUNY Upstate Medical University, Syracuse, New York.

Importance: Intermittent explosive disorder (IED) is an understudied psychiatric condition marked by impulsive aggression and poorly regulated emotional control, often resulting in interpersonal and societal consequences. Better understanding of comorbidities can improve screening, diagnosis, and treatment.

Objective: To investigate the prevalence of IED and its associations with psychiatric, neurological, and somatic disorders.

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Background And Aims: Sexual trauma is associated with multiple negative health and social conditions, including compulsive sexual behavior. The present study examined network structures involving sexual trauma history, psychological distress (defined as depression and/or anxiety symptoms), substance use, transactional sex, and compulsive sexual behavior. Prior network analysis work in this area is limited.

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This study is the first to explore the relation between children's attachment classifications, assessed by Mary Ainsworth's Strange Situation Procedure (SSP), and mothers' acceptance-rejection behaviors from the lens of Interpersonal Acceptance-Rejection Theory (IPARTheory). As a pilot study, the sample consisted of 23 Egyptian mother-child dyads. The mean age of children in the SSP was 18.

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Triple-negative breast cancer (TNBC) is the most lethal and aggressive breast cancer among all the breast cancer subtypes. Despite several attempts, to date, there is an extensive lack of therapeutic intervention. Hence, there is a dire need for an effective biomarker to timely diagnose TNBC.

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Background: Existing studies on breast cancer survivors (BCS) have primarily focused on individual aspects of either diet or exercise preferences and barriers. Our study aims to examine BCS' perceptions toward diet and exercise combined. Given the transformative impact of COVID-19, there is a crucial need for insights in the post-pandemic era to address the distinct challenges faced by BCS in maintaining their health and well-being.

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