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Neurobehavioral Disorders and Pathological Changes in the Brain of Mice Are Caused by Chronic Toxocara canis Larval Invasion with Low to Moderate Inoculum.
Acta Parasitol
December 2024
Institute of Immunology and Microbiology, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czechia.
Toxocara canis larvae are one of the most overlooked agents of nervous system infection in paratenic hosts. Previous studies in mouse models have shown that infection with various (mainly high) numbers of larvae leads to neurobehavioral disturbances and pathological changes. Our study investigated whether the infection with low and moderate numbers of larvae could affect the physical condition, motor skills, and pathogenesis in the brains of experimentally infected mice.
View Article and Find Full Text PDFThe impact of Toxocara-seropositivity on attention and motor skills in children with attention-deficit hyperactivity disorder.
Early Hum Dev
June 2024
Aydın Adnan Menderes University, Department of Parasitology, Aydın, Turkiye.
Background: The study aims to compare neurological soft signs and executive functions between Toxocara-seropositive and seronegative groups in children with attention-deficit/hyperactivity disorder.
Methods: The study included 60 boys with ADHD, aged 7-12. After blood samples were taken, the Stroop Color Word Test and Judgment of Line Orientation test (JLOT) were implemented to measure executive functions.
Migratory pattern of zoonotic Toxocara cati and T. canis in experimentally infected pigs.
Eur J Clin Microbiol Infect Dis
March 2024
Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus N, 8200, Aarhus, Denmark.
Background: Over a billion people are infected with Toxocara canis or T. cati, the roundworms of dogs and cats. Historically, T.
View Article and Find Full Text PDFImmunomodulation in the intestinal mucosa of mice supplemented with Lactobacillus rhamnosus (ATCC 7469) and infected with Toxocara canis.
Immunobiology
May 2023
Post-Graduate Program in Health Sciences - Parasitology Laboratory, Federal Univesity of Rio Grande (FURG), Rio Grande, Rio Grande do Sul, Brazil.
Toxocariasis is an anthropozoonosis caused by the helminth Toxocara canis that shows different clinical manifestations as visceral, ocular, or neurological toxocariasis forms. Probiotics have been studied as alternatives to prevent and treat this parasitosis. Lactobacillus rhamnosus is a prospect that presents immunomodulatory activity that acts to strengthen the intestinal barrier.
View Article and Find Full Text PDFA case report of spinal toxocariasis with extensive tumor-like involvement.
Childs Nerv Syst
March 2023
Department of Rehabilitation Medicine, Seoul National University Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, 03080, Republic of Korea.
Background: Toxocariasis is a common parasitic infection worldwide. Although it can present as several clinical syndromes, neurological manifestation is rare. Only a few reports are available on spinal cord involvement of toxocariasis.
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