The paper is concerned with comparative estimation of the effect of different therapeutic methods (hypocaloric diet, physiotherapeutic, drug and exercise therapy, reflexotherapy) on loss of body mass. The experience of reflexotherapy of 86 patients showed its positive effect on the psychoemotional activities of patients with obesity, a rise of adaptation capabilities of the body under physical exercise, improved external respiration function, an increase in oxygen saturation of tissues, the stimulation of metabolism (by the basal metabolism findings) by way of increasing the secretion of hypophyseal tropic hormones, triiodothyronine and thyroxin, and potentiation of the time course of loss of body mass.

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