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Anorexia nervosa in children and adolescents: an early detection of risk factors.
Ital J Pediatr
October 2024
The Italian Pediatric Society Adolescent Study Group, The Italian Pediatric Society, Rome, Italy.
The incidence of eating disorders in children, mainly of anorexia nervosa, is dramatically increased in the last years. A timely identification of the disease is associated with higher rates of recovery. Aim of the work is to underline signs and symptoms that can be used to an early detection of anorexia nervosa in the pediatric age.
View Article and Find Full Text PDFAbdominal aorta intima-media thickness in children with hypothyroidism.
Pediatr Neonatol
September 2024
Pediatrics Department, Faculty of Medicine, Cairo University, Giza, Egypt.
Hypothyroidism is associated with atherosclerosis, which is attributed mainly to an atherogenic lipid profile. Increased intima-media thickness (IMT) is the first structural change detected in atherosclerosis. This prospective cohort study investigated lipid profile and abdominal aorta IMT in patients newly-diagnosed with hypothyroidism and their change one year post-treatment.
View Article and Find Full Text PDFOrganokines and liver enzymes in adolescent girls with polycystic ovary syndrome during randomized treatments.
Front Endocrinol (Lausanne)
May 2024
Endocrinology Department, Institut de Recerca Sant Joan de Déu, University of Barcelona, Barcelona, Spain.
Introduction: Polycystic ovary syndrome (PCOS) is often associated with metabolic-associated fatty liver disease (MAFLD). MAFLD has been associated with altered hepatic function, systemic dysmetabolism, and abnormal circulating levels of signaling molecules called organokines. Here, we assessed the effects of two randomized treatments on a set of organokines in adolescent girls with PCOS and without obesity, and report the associations with circulating biomarkers of liver damage, which were assessed longitudinally in the aforementioned studies as safety markers.
View Article and Find Full Text PDFAssessment of Cardiovascular Function in Childhood Leukemia Survivors: The Role of the Right Heart.
Children (Basel)
November 2022
Department of Pediatric Oncology and Hematology, University Hospital of Policlinico, 70124 Bari, Italy.
Childhood acute lymphoblastic leukemia (ALL) survivors who underwent chemotherapy with anthracyclines have an increased cardiovascular risk. The aim of the study was to evaluate left and right cardiac chamber performances and vascular endothelial function in childhood ALL survivors. Fifty-four ALL survivors and 37 healthy controls were enrolled.
View Article and Find Full Text PDFResponse of South Indian girls with central precocious puberty to gonadotrophin analogue (GnRHa) therapy - a single center experience.
Pediatr Endocrinol Diabetes Metab
February 2022
Department of Pediatrics, Mehta Multispeciality Hospitals India Pvt Ltd, India.
Aim Of The Study: To describe the clinical, auxological, biochemical and radiological response to GnRH analogue in female children with central precocious puberty (CPP).
Material And Methods: The data on 22 female children presenting with the larche < 8 years, pubarche < 8 years or menarche < 9 years diagnosed as CPP was collected from the records over a four year period. Assessment included growth parameters, Tanners staging; bone age (BA) by Greulich and Pyle method, ultrasonography of abdomen to assess uterine length and ovarian size and z score derived; biochemical evaluation included serum luteinising hormone (LH), follicle stimulating hormone (FSH) and estradiol (E2); and MRI brain.
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