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(68)Ga-radiopharmaceuticals for PET imaging of infection and inflammation.

Recent Results Cancer Res

June 2013

Department of Nuclear Medicine, The Children's Hospital at Westmead, Westmead, Australia.

Infection imaging has been challenging over the past four decades, which provided an excellent playing field for researchers working in this area, and till date the quest continues to find an ideal imaging agent. Labelled leukocytes were first developed in the 1970s for imaging infection lesions such as osteomyelitis, cellulitis, diabetic foot, Crohn's disease, inflammatory bowel disease, fever of unknown origin, etc. Subsequently labelled antibiotics such as (99m)Tc-labelled ciprofloxacin have emerged for directly identifying live bacterial infections.

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Lumbosacral epidural abscess as a complication of post-injection phlegmon of the forearm. Case report.

Ann Acad Med Stetin

October 2011

Klinika Neurochirurgii i Neurochirurgii Dzieciecej Pomorskiej Akademii Medycznej w Szczecinie ul. Unii Lubelskiej 1, 71-252 Szczecin.

We present the case of a 50-year-old male with lumbosacral epidural abscess as a distant iatrogenic sequella of a post-injection phlegmon of the forearm. The progressive and inconspicuous course of the illness, its complex clinical picture, neurologic manifestation in the form of cauda equina syndrome, and multidisciplinary approach to diagnosis and treatment in this patient make this case worthy of particular attention. We decided on a combined therapy consisting of surgery and pathogen-directed antibiotic treatment.

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Interpretation of lymphoscintigrams in suspected lymphoedema: contribution of delayed images.

Nucl Med Commun

August 1995

Department of Nuclear Medicine and Ultrasound, Westmead Hospital, New South Wales, Australia.

Interpretation of lymphoscintigrams in patients with extremity oedema may be adversely affected by any variation in the acquisition protocol. The purpose of this study was to determine whether delayed (2-24 h post-injection) views provide information incremental to the first 60 min of acquisition. In a 5-year period, 31 patients (10 males, 21 females, mean age 46 years) with extremity oedema or recurrent cellulitis underwent lymphoscintigraphy using 99Tcm-antimony trisulphide colloid (99Tcm-Sb2S3).

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The work presents results of treatment of 1019 patients aged from 20 to 89 with postinjectional phlegmons. Operations were made on 1003 patients. Main causes of the appearance of the disease, choice of anesthesia and modern methods of treatment are discussed.

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The observation of 32 patients has shown that the presence of all kinds of hypoxia in iatrogenic sepsis determines the complex therapy aimed at all the links of the pathogenetic chain associated with hyperbaric oxygenation. The debridement of the wounds from necrotic patches, appearance of pink granulations were noticed after 5-6 sessions of HBO which could be followed by skin plasty. The following 7-14 sessions of HBO resulted in a good take of the transplanted grafts.

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