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Functional nano drug delivery system with dual lubrication and immune escape for treating osteoarthritis.
J Colloid Interface Sci
December 2023
School of Materials Science and Engineering, South China University of Technology, Guangzhou 510006, China; National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510006, China; Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education, South China University of Technology, Guangzhou 510006, China; Key Laboratory of Biomedical Engineering of Guangdong Province, South China University of Technology, Guangzhou 510006, China; Innovation Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China. Electronic address:
Local drug delivery via inter-articular injection offers a promising scenario to treat the most common joint disease, osteoarthritis (OA), which is closely associated with the increased friction or cartilage degeneration and the inflammatory syndrome of synovium. Therefore, it is quite necessary to improve the retention of drug delivery system within synovial joint, simultaneously restore the lubrication of degraded cartilage and meanwhile alleviate the inflammation. In this study, we propose a hydrophilic coating modified nano-liposome drug carrier (PMPC-Lipo) to achieve these functions.
View Article and Find Full Text PDFThree-Dimensional Upper Body Kinematics and Inter-articular Kinematic Sequence During a Canoe Polo Throw.
Front Sports Act Living
December 2021
Univ Lyon, Université Claude Bernard Lyon 1, Univ Gustave Eiffel, LBMC UMR_T9406, Lyon, France.
Canoe polo is an increasingly popular discipline requiring both kayaking and ball-handling skills. While the kinematics of the upper body during throw has been investigated for several overhead sports, the canoe polo throw has still to be studied. Therefore, the aim of this study is to analyze the canoe polo throw kinematics in terms of angles and inter-articular sequencing to understand its specificity.
View Article and Find Full Text PDFEfficacy of suprascapular nerve blocks for management of hemiplegic shoulder pain: a systematic review and meta-analysis.
Eur Rev Med Pharmacol Sci
July 2021
Department of Rehabilitation, Hwa Mei Hospital, University of Chinese Academy of Sciences; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, Zhejiang Province, China.
Objective: To compare the efficacy of suprascapular nerve block (SSNB) with other treatment modalities for management of HSP in terms of relieving pain and improving range of motion of shoulder joints.
Materials And Methods: An electronic search was carried out in PubMed, CENTRAL, SCOPUS and EMBASE databases using a series of relevant keywords, along with a manual search. Randomized clinical trials comparing the efficacy of SSNB with placebo injections, intra-articular injections (IAI), ultrasound and Pulsed RF were identified.
Controversies in the surgical management of congenital craniocervical junction disorders - A critical review.
Neurol India
September 2019
Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Introduction: Congenital disorders of the craniovertebral junction (CVJ) include a wide range of conditions, such as Chiari malformation (CM), basilar Invagination (BI), and atlantoaxial dislocation (AAD). The objective of this paper is to critically review the literature related to the management of congenital CVJ disorders focusing on: the significant developments in the past (from anterior open ventral decompression to modern CVJ realignment); the diagnosis of CVJ instability; the role of atlantoaxial fixation without posterior fossa decompression in patients with tonsillar herniation and no evidence of CVJ instability; use of C1-2 inter-articular spacers and use of C1-2 interarticular spacers with intra-operative manipulations to correct BI with AAD along with its deformity.
Materials And Methods: We performed a review of articles showing up on PubMed database without time restriction.
Vibration transfer in the ball-stem contact interface of artificial hips.
Med Eng Phys
October 2013
TUHH - Hamburg University of Technology, Institute of Biomechanics, Denickestrasse 15, 21073 Hamburg, Germany.
Audible squeaking has put the reputation of ceramic bearings for total hip replacements into question. Inter-articular friction induces vibrations in the ceramic head which are transferred through the head-taper interface to the femoral stem. If excited to sufficient amplitudes, squeaking can be emitted by the stem.
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