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Correlation of bioscintigraphy, contrast venography, and iodine-125 fibrinogen uptake test. | LitMetric

AI Article Synopsis

  • In a study of 40 patients suspected of having deep venous thrombosis (DVT), bioscintigrams using I-123 fibrinogen were compared with traditional methods like contrast venograms and I-125 fibrinogen uptake tests.
  • The accuracy of bioscintigraphic imaging was found to be 90% when either of the standard methods was used for comparison.
  • The study indicated that bioscintigraphy is a promising noninvasive tool for detecting DVT and can help differentiate it from other conditions causing localized radioactivity.

Article Abstract

In 40 patients believed to have deep venous thrombosis, bioscintigrams performed with I-123 fibrinogen were available for comparison with either contrast venograms or I-125 fibrinogen uptake tests. If either contrast venography or the fibrinogen uptake test was accepted as a standard for comparison, the accuracy of bioscintigraphic imaging was 90%. Most discrepancies between the procedures could be interpreted as due to heparin treatment, although bioscintigrams often were positive in patients treated with heparin for a short interval of time. Additionally, bioscintigrams provided information to distinguish venous thrombosis from other sources for local accumulation of radioactivity. Bioscintigraphy seems to be a promising noninvasive method for the detection of deep venous thrombosis of the lower extremities.

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Source
http://dx.doi.org/10.1097/00003072-198512000-00013DOI Listing

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