On the basis of the analysis of the described cooling regime of biological objects during low temperature preservation it is suggested that an optimal regime should have non-linear dependence of the rate of temperature change in time. By approximation of several experimental cooling regimes it is found that the exponential description of this process is the most correct. Advantages of using the exponential cooling regime instead of the linear ones during their optimization are grounded. The theoretical premises of the exponential cooling regime realization are described.
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