[The therapeutic system, CODIC].

CODIC-COmputeriseD Infusion Control is the first universally applicable therapeutic system which can be programmed by the user. CODIC consists of a monitoring unit for IMED 929 infusion pump. It is the first open therapeutic system in the "no demand" mode which is not only programmed but can also be programmed and modified by the user. This makes it universally applicable. It was mainly developed for highly effective drugs with a narrow therapeutic range and short half-life. CODIC opens up possibilities for the optimisation of advanced drug therapy which had not existed so far (e.g. cytostatics). If operated in the "on demand" mode via a pushbutton pressed down by the patient according to individual requirements by analgesic boluses, CODIC provides freedom from pain (not only postoperatively). The fixed-programme infusion profile prevents excess dosage. The same applies to pain relief during child birth. CODIC has been in routine use by the author for the last two years, especially for the automatic monitoring of infusions of Tramadol, Nalbuphin or NLA substances in combination anaesthesia, or in controlled hypotension with nitroprusside.