Many of today's jobs involve repetitive tasks, often resulting in mechanical trauma to the skin. Trauma from pressure, pounding, friction, vibration, and penetration of foreign materials produce a great variety of skin lesions. Mechanical insults contribute directly or indirectly to a number of distinctive problems that are work related, viz, infections, contact dermatitis, occupational skin stigmata, reactions to unabsorbable materials, vibration effects, dermatoses among athletes, the Koebner phenomenon in palmar psoriasis, pressure urticaria, and cutaneous neoplasms arising in burns and scars.
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http://dx.doi.org/10.1002/ajim.4700080404 | DOI Listing |
J Hand Ther
March 2025
Leon Root, MD Motion Analysis Laboratory, Department of Rehabilitation, Hospital for Special Surgery, New York, NY, USA. Electronic address:
Background: This easibility cohort study follows a prior randomized control pilot trial that examined the feasibility and impact of a formal Musculoskeletal Health for Musicians (MHM) program. In this follow-up study, an expanded program was designed to target hand and arm pain by adding exercises for the wrist, elbow, forearm, and hand intrinsic muscles. The MHM program combines education with exercise instruction to prevent pain and injury in musicians.
View Article and Find Full Text PDFContemp Clin Trials
March 2025
Department of Anesthesia and Critical Care, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Background: Pulmonary fibrosis is a major complication of the Acute Respiratory Distress Syndrome (ARDS). Pirfenidone is an approved treatment for idiopathic pulmonary fibrosis. It may attenuate ARDS-related fibrosis and decrease the need for prolonged ventilation.
View Article and Find Full Text PDFInt J Biol Macromol
March 2025
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei Province, PR China; Wuhan University Shenzhen Research Institute, Shenzhen 518000, Guangdong Province, PR China. Electronic address:
Corneal fibrosis, a severe complication linked to ocular injuries and post-surgery, lacks effective treatment. Hydrogels are regarded as one of the most promising biomaterials, particularly in the context of corneal wound treatment, where they have attracted considerable attention. Synthetic protein hydrogels are of particular interest due to their biocompatibility, biodegradability, capacity to mitigate induced tissue inflammatory responses, and their editable and modular integrative properties.
View Article and Find Full Text PDFJ Control Release
March 2025
State Key Laboratory of Digital Medical Engineering, National Demonstration Center for Experimental Biomedical Engineering Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China; Institute of Medical Devices (Suzhou), Southeast University, 3rd Floor, Building 1, Medpark, No.8 Jinfeng Road, Suzhou 215163, China. Electronic address:
Abdominal wall defects caused by trauma, congenital rupture, and intra-abdominal infection remain challenging due to the large wound area and complex complications. Herein, an assembled mesenchymal stem cell (MSCs)-laden granular hydrogel (termed assembled GSD@FPs), loaded with basic fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF), was developed. This hydrogel was constructed through dynamic covalent cross-linking (via borate ester bonds) among dopamine-grafted gelatin methacrylamide (GelMA-DA), phenylborate-modified hyaluronic acid (HA-PBA), and epigallocatechin-3-gallate (EGCG), serving as multifunctional bulk building blocks for cell delivery and abdominal wall repair.
View Article and Find Full Text PDFActa Biomater
March 2025
Department of Mechanical Engineering, University of Utah, Salt Lake City, UT, USA; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA. Electronic address:
Traumatic brain injury poses a major public health challenge with significant immediate and long-term effects. Repetitive head trauma is an ongoing area of research, and little is known about the response of cerebral blood vessels to such loading. This study investigated the mechanical response of cerebral arteries to repetitive overstretch, hypothesizing that repeated overstretch leads to cumulative damage.
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