The paper is devoted to the organization, theory and practice of gerontological pathopsychology, including questions of differentiation between normal and pathological in gerontopsychiatry, validity and reliability of experimental-psychological methods. With special reference to a variety of forms of the insight of the disease in elderly age the author shows a multi-factorial nature of personality symptom complexes. The design of a pathopsychological study and the selection of experimental techniques are shown to depend on the nature of clinical tasks facing the investigator.
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Heliyon
October 2024
Department of Neurology, Albert Szent-Györgyi Clinical Center and Faculty of Medicine, University of Szeged, Szeged, Hungary.
Introduction: Natalizumab (NAT), a highly effective disease modifying therapy (DMT) in relapsing-remitting multiple sclerosis (RRMS), was approved for clinical use in Hungary on February 1, 2010. In this study we aimed to assess its effectiveness in view of the concept of "No Evidence of Disease Activity" (NEDA-3), furthermore evaluate its effect on limb function, pathopsychological symptoms (cognition, fatigue, depression) and quality of life (QoL).
Patients And Methods: From February 1, 2010, to December 1, 2022, 121 eligible patients were consecutively enrolled from the MS center of the University of Szeged, Hungary.
Molecules
June 2021
Albert Szent-Györgyi Clinical Centre, Department of Neurology, Faculty of General Medicine, University of Szeged, H-6725 Szeged, Hungary.
Neurodegeneration is one of the driving forces behind the pathogenesis of multiple sclerosis (MS). Progression without activity, pathopsychological disturbances (cognitive impairment, depression, fatigue) and even optic neuropathy seems to be mainly routed in this mechanism. In this article, we aim to give a comprehensive review of the clinical aspects and symptomology, radiological and molecular markers and potential therapeutic targets of neurodegeneration in connection with MS.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
April 2019
Priorov Central Institute of Traumatology and Orthopaedics, Moscow, Russia.
Low back pain is one of the most common causes of disability in the world. Discogenic process is the leading component of the disease. A significant part of these pain syndromes become chronic that leads to disability and social maladjustment.
View Article and Find Full Text PDFObesity (Silver Spring)
February 2015
Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Germany; Leipzig University Medical Center, IFB Adiposity Diseases, Leipzig, Germany; Mailman School of Public Health, Department of Epidemiology, Columbia University, New York City, New York, USA.
Objective: Research consistently shows a negative view of individuals with obesity in the general public and in various other settings. Stigma and discrimination can be considered chronic stressors, as these factors have a profound impact on the psychological well-being of the affected individuals. This article proposes a framework that entails a mediation of the adverse effects of discrimination and stigmatization on mental well-being through elevated psychological risk factors that are not unique to weight but that could affect overweight and normal-weight individuals alike.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!