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Minimally invasive treatments for chronic low back pain.

JAAPA

December 2024

At the time this article was written, Chelsey M. Hoffmann was academic co-director of the PA program at the Mayo Clinic School of Health Science in Rochester, Minn. She now practices in the Department of Pain Medicine, Division of Anesthesiology, at the Mayo Clinic in Rochester, Minn. Ryan Mattie practices at Total Spine Institute in Los Angeles, Calif. Samir J. Sheth practices at Sutter Health in Roseville, Calif. Ryan S. D'Souza is director of neuromodulation and a consultant in the Department of Pain Medicine, Division of Anesthesiology, at the Mayo Clinic. Ms. Hoffmann discloses that she provides general consulting for SPR Therapeutics and Nalu Medical. Dr. Sheth is a consultant for SPR, Medtronic, Boston Scientific, and Vertos. Dr. D'Souza has an investigator-initiated grant with Nevro Corp. The authors have disclosed no other potential conflicts of interest, financial or otherwise.

This article describes minimally invasive treatments for managing chronic low back pain (LBP) related to lumbar spinal stenosis, facetogenic LBP, vertebrogenic LBP, or discogenic LBP. We also propose a clinical decision-making tool to guide clinicians in appropriate patient selection for various treatments.

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Basivertebral nerve ablation technique.

Tech Vasc Interv Radiol

September 2024

University of Alabama Birmingham School of Medicine Department, Division of Vascular and Interventional Radiology, Birmingham, AL.

Chronic low back pain represents a leading cause of global disability, but can often be complex in etiology, with multiple pain generators contributing to patient discomfort. Anterior column low back pain involves the vertebral bodies and discs, with the vertebral body endplates now known to be a significant pain generator. Vertebrogenic low back pain secondary to irritation of the basivertebral nerve presents as axial discomfort, worse with forward flexion, and with concomitant Type I or II Modic changes on MRI.

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Lower back pain (LBP) is a widely prevalent global health issue, affecting over half a billion people and remaining the leading cause of years lived with disability (YLDs). LBP significantly impacts healthcare systems, with substantial costs related to surgical procedures and lost workdays. Vertebrogenic back pain (VBP), characterized by specific clinical symptoms and associated with Modic changes (MC) in vertebral endplates, best seen on MRI, is a significant subset of LBP.

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Chronic Low Back Pain: History, Symptoms, Pain Mechanisms, and Treatment.

Life (Basel)

June 2024

Center for Spine Health, Neurological Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA.

Article Synopsis
  • Chronic low back pain (cLBP) is a leading cause of disability, making it essential to pinpoint the underlying anatomical issues for effective treatment.
  • The causes of cLBP are diverse, ranging from non-degenerative factors like trauma and inflammation to degenerative conditions that require careful evaluation to rule out serious underlying issues.
  • The article outlines a systematic approach for clinicians by categorizing the potential structures involved in cLBP, offering insights into diagnostic methods and treatment options for each condition.
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Objective: Based on an analysis of modern medical literature, to study the main clinical characteristics of pain in patients with transitional lumbosacral vertebrae.

Material And Methods: A search was made for articles in the scientific electronic libraries CYBERLENINKA, eLIBRARY, Google Scholar, and the electronic database of biomedical publications PubMed. Sixty-eight scientific publications corresponded to the stated goal.

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