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Toxic Plants and Their Impact on Livestock Health and Economic Losses: A Comprehensive Review.
J Toxicol
December 2024
Ambo University, Guder Mamo Mezemir Campus, Department of Veterinary Science, West Shewa Zone, Oromia, Ethiopia.
Plants are important components in sustaining the life of humans and animals, balancing ecosystems, providing animal feed and edible food for human consumption, and serving as sources of traditional and modern medicine. However, plants can be harmful to both animals and humans when ingested, leading to poisoning regardless of the quantity consumed. This presents significant risks to livestock health and can impede economic growth.
View Article and Find Full Text PDFpoisoning in a horse - A case report.
Vet Med (Praha)
September 2024
Equine Clinic, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czech Republic.
Article Synopsis
- The study details the first confirmed case of pyrrolizidine alkaloid poisoning in a horse, specifically a six-year-old Irish cob mare that exhibited severe liver damage leading to euthanasia.
- Despite intensive treatment, the mare's condition worsened, with post-mortem examinations revealing significant liver damage and the presence of pyrrolizidine alkaloid metabolites in her tissues.
- The findings suggest that typical histopathological signs of pyrrolizidine alkaloid poisoning may not always be present, highlighting the complexity of diagnosing this type of poisoning in equine patients.
Regulatory role of oxidative stress in retrorsine - Induced apoptosis and autophagy in primary rat hepatocytes.
Ecotoxicol Environ Saf
July 2024
College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address:
Pyrrolizidine alkaloids (PAs) are a group of naturally occurring alkaloids widely present in plants. PAs are highly hepatotoxic and have been documented to cause many incidents of human and animal poisoning. Retrorsine (RTS) is a pyrrolizidine alkaloid (PA) derived from the Compositae Senecio, which has been shown to cause hepatotoxicity.
View Article and Find Full Text PDFMetabolite Profiling in the Liver, Plasma and Milk of Dairy Cows Exposed to Tansy Ragwort () Pyrrolizidine Alkaloids.
Toxins (Basel)
October 2023
Institute of Animal Nutrition, Friedrich-Loeffler-Institute, 38116 Braunschweig, Germany.
Background: Plant-derived pyrrolizidine alkaloids (PAs) in feed cause metabolic disturbances in farm animals resulting in high economic losses worldwide. The molecular pathways affected by these PAs in cells and tissues are not yet fully understood. The objective of the study was to examine the dose-dependent effects of orally applied PAs derived from tansy ragwort in midlactation dairy cows.
View Article and Find Full Text PDFChemical Management of (Fireweed).
Plants (Basel)
March 2023
School of Agriculture and Food Science, University of Queensland, Gatton Campus, 4343, QLD, Australia.
Fireweed ( Poir.) is a herbaceous weed-producing pyrrolizidine alkaloid that is poisonous to livestock. To investigate the efficacy of chemical management on fireweed and its soil seed bank density, a field experiment was conducted in Beechmont, Queensland, in 2018 within a pasture community.
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