The authors stress the importance of a local theta-rhythm first described by Chatrian in 1953 and largely neglected by clinical electroencephalographers. This rhythm is constituted of waves at 3-5 c/sec; it is localised on the anterior temporal region in one hemisphere and has the same value as isolated temporal spikes or spike-waves for the diagnosis of temporal epilepsy. It furthermore presents the advantage of being specific for a particular form of temporal epilepsy of precocious appearance subsequent to a sclerosis of the anterior median temporal cortex acquired at birth or in early childhood.
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http://dx.doi.org/10.1016/s0370-4475(85)80015-0 | DOI Listing |
Sci Rep
January 2025
Department of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Dalian Road 149, Huichuan District, Zunyi, 563000, Guizhou Province, China.
The aim of the study was to evaluate the concomitant psychiatric disorders of anxiety and depression in patients with epilepsy caused by low-grade brain tumors (LBTs). We retrospectively reviewed the clinical data of patients who underwent preoperative neuropsychological evaluations of anxiety and depression and subsequent epilepsy surgery for LBTs. The univariate and multivariate analyses were conducted to analyze the risk factors of the occurrence of anxiety and depression.
View Article and Find Full Text PDFBackground: Altered network synchronization and rhythmic neural activity is observed in Alzheimer's disease (AD). Spontaneous epileptiform activity and/or seizures occur in an estimated 60% of AD cases, and having AD increases the likelihood of seizures when compared with people without dementia. Thus, network hyperexcitability can be an early feature and helpful for diagnosis and treatment.
View Article and Find Full Text PDFBackground: There is an increased risk of epilepsy in Down syndrome (DS), especially after the age of 40. The onset of this co-occurring disease is closely associated with Alzheimer's disease (AD) related cognitive deterioration. Therefore, understanding the impact of late-onset epilepsy on AD biomarkers in people with DS is crucial.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Douglas Mental Health University Institute, Montreal, QC, Canada.
Background: Classical literature has pointed at lateralization of the relationship between memory scores and cerebral hemisphere injury. Epilepsy studies have suggested an association between left hippocampal damage and verbal memory deficits, and between right hippocampal damage and visual memory deficits. We aimed to explore this concept in the context of tauopathy due to Alzheimer's disease.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, Irvine, Irvine, CA, USA.
Background: There is an increased risk of epilepsy in Down syndrome (DS), especially after the age of 40. The onset of this co-occurring disease is closely associated with Alzheimer's disease (AD) related cognitive deterioration. Therefore, understanding the impact of late-onset epilepsy on AD biomarkers in people with DS is crucial.
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