In this study of the young chick we examine the effects of unilateral or bilateral eye enucleation on the number of axons in the supraoptic decussation, a major interhemispheric tract subserving visual function. On posthatch day 25, chicks underwent removal of either one or both eyes. After a survival period of 32 days, electron microscopic examination of the supraoptic decussation revealed a substantial loss of fibres. In the bilaterally enucleated group, a significant decrease in the number of axons occurred in both the dorsal and ventral aspects of the supraoptic decussation. The effect of unilateral enucleation was not as severe. The results indicate that enucleation of the precocial and functioning visual system of the chick leads to a transneuronal loss of axons. The degree of loss may reflect the amount of fibres in the crossed visual projection within the supraoptic decussation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0304-3940(85)90602-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of serotonergic projections to the suprachiasmatic nucleus in the mouse brain.
Neurosci Lett
November 2020
RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan; Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338-8570, Japan; Department of Physiology and Cell Biology, Kobe University School of Medicine, Chuo, Kobe 650-0017, Japan. Electronic address:
Serotonin (5-HT) and its innervation have been implicated in various neural functions including circadian systems. Although classical studies have examined the 5-HT innervation pattern in the adult suprachiasmatic nucleus (SCN), the fine-grained morphological study of the development of pathway and terminal projections to the SCN remains scarce. Here, we utilize transgenic mice expressing GFP under the serotonin transporter (SERT) promoter to subserve our developmental mapping study.
View Article and Find Full Text PDFNuclear derivatives and axonal projections originating from rhombomere 4 in the mouse hindbrain.
Brain Struct Funct
November 2017
Department of Human Anatomy and Psychobiology, Faculty of Medicine, University of Murcia, 30071, Murcia, Spain.
The r4-derived territory is located in the pontine region of the brainstem, forming a wedge-shaped slice that broadens from the choroidal roof to the ventral midline. R4-derived neuronal populations migrate radially inside and tangentially outside this rhombomere, forming nuclei of the sensorimotor auditory, vestibular, trigeminal and reticular systems. R4-derived fibre tracts contribute to the lateral lemniscus, the trigeminothalamic tracts, the medial tegmental tract and the medial forebrain bundle, which variously project to the midbrain, thalamus, hypothalamus and telencephalon.
View Article and Find Full Text PDFTuberoinfundibular peptide of 39 residues- immunoreactive fibers in the zona incerta and the supraoptic decussations terminate in the neuroendocrine hypothalamus.
Neurochem Res
December 2010
Neuromorphological and Neuroendocrine Research Laboratory, Department of Anatomy, Histology and Embryology, Semmelweis University and The Hungarian Academy of Sciences, Tüzoltó-utca 58, 1094 Budapest, Hungary.
Tuberoinfundibular peptide of 39 residues (TIP39) is expressed by neurons in the subparafascicular area, the posterior intralaminar complex of the thalamus and the pontine medial paralemniscal nucleus. TIP39-positive fibers from these areas do not form individual bundles or fascicles, they join other pathways to reach their innervated brain areas. Fibers arise from TIP39 perikarya located in the subparafascicular area and the posterior intralaminar complex of the thalamus could be followed to the hypothalamus.
View Article and Find Full Text PDFTuberoinfundibular peptide of 39 residues in the embryonic and early postnatal rat brain.
J Chem Neuroanat
September 2008
Neuromorphological and Neuroendocrine Research Laboratory, Department of Anatomy, Histology and Embryology, Semmelweis University and the Hungarian Academy of Sciences, Budapest H-1094, Hungary.
Tuberoinfundibular peptide of 39 residues (TIP39) was identified as the endogenous ligand of parathyroid hormone 2 receptor. We have recently demonstrated that TIP39 expression in adult rat brain is confined to the subparafascicular area of the thalamus with a few cells extending laterally into the posterior intralaminar thalamic nucleus (PIL), and the medial paralemniscal nucleus (MPL) in the lateral pontomesencephalic tegmentum. During postnatal development, TIP39 expression increases until postnatal day 33 (PND-33), then decreases, and almost completely disappears by PND-125.
View Article and Find Full Text PDFCalcitonin gene-related peptide-containing pathways in the rat forebrain.
J Comp Neurol
August 2005
Laboratory of Genetics, National Institutes of Mental Health, Bethesda, Maryland 20892, USA.
The present study focuses on the topographical distribution of calcitonin gene-related peptide (CGRP)-containing cell bodies and fibers and their connections and pathways in the rat forebrain. We confirm previously reported CGRP projections from the perifornical area of the hypothalamus to the lateral septum, from the posterior thalamus to the caudate putamen and cerebral cortex, and from the parabrachial nuclei to the central extended amygdala, lateral hypothalamus, and ventromedial thalamus. Despite previous descriptions of CGRP in the central nervous system, important neuroanatomical aspects of the forebrain CGRP system remained obscure, which we addressed by using brain lesion techniques combined with modern immunohistology.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!