A segmented polyurethane prosthetic anterior cruciate ligament prototype has been developed and its in vivo integrity assessed in canine subjects. Prosthetic ligaments surgically implanted for 3, 4, 6, 8, 12, and 16 months were assessed clinically in living subjects, at time of autopsy, and microscopically postautopsy. It was found that the ligaments were adequate in strength to provide stability and last for periods up to 16 months. Notching of the ligaments was observed at two designated friction points.
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