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Post-COVID immunity in patients with solid tumor or hematological malignancies treated with SARS-CoV-2 monoclonal antibodies.
Immun Inflamm Dis
December 2024
Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Article Synopsis
- - The study investigates how SARS-CoV-2 monoclonal antibody (mAB) therapy affects the immune response in five cancer patients infected with the virus, comparing them to non-mAB-treated controls.
- - Blood samples were analyzed for various immune responses, revealing that all patients produced antibodies and T-cell responses similar to those of controls, despite some having B-cell deficiencies.
- - The findings indicate that mAB therapy results in a robust immune response against SARS-CoV-2 in cancer patients, showing the potential for effective protective immunity even with underlying malignancies.
A clinical case of B-cell lymphoma in a Japanese Black cow with monoclonal proliferation of B-cells as revealed by polymerase chain reaction based on the immunoglobulin light chain gene.
J Vet Med Sci
December 2024
Laboratory of Farm Animal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
A 35-month-old Japanese Black cow was presented to a local veterinarian with a main complaint of premature labor. There was no swelling of lymph nodes on the body surface and no palpable mass on rectal examination. Although atypical lymphocytes were observed in the peripheral blood, no lymphocytosis was recorded.
View Article and Find Full Text PDFHaizao-Gancao herb pair ameliorates propylthiouracil-induced goiter by regulating the Beclin1-mediated autophagy.
J Ethnopharmacol
January 2025
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address:
Ethnopharmacological Relevance: Haizao, Sargassum, is widely used to treat goiter. Gancao, Glycyrrhizae radix et rhizome, is renowned for reducing toxicity or increasing effects in traditional Chinese medicine. As a classic herb pair, Haizao-Gancao (HG) is a commonly used and effective combined therapy for goiter.
View Article and Find Full Text PDFCost analysis of anticancer chemotherapy and chemoirradiation regimens considering the drugs marketed through Jan Aushadhi (People's Medicine) stores and their branded counterparts: First cost comparison study.
J Cancer Res Ther
July 2024
Research Department, Mangalore Institute of Oncology, Mangalore, Karnataka, India.
Article Synopsis
- Chemotherapy is crucial for cancer treatment but is often too expensive; the Indian government launched Jan Aushadhi (JAS) stores to provide affordable generic medicines.
- The study aimed to compare the costs of chemotherapy regimens using JAS drugs, as well as the most and least expensive branded drugs in India.
- Results showed substantial cost differences when using JAS drugs for chemotherapy across various types of cancers, indicating potential savings for patients.
Incidence of intestinal & extra-intestinal cancers among individuals with Crohn's disease in northern India.
Indian J Med Res
July 2024
Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- Crohn's disease (CD) is linked to an increased risk of cancer, partly due to disease characteristics and immunosuppressive treatment; this study focuses on data from a northern Indian cohort to shed light on CD-related malignancies in Asia.
- A total of 952 participants, with a mean age of 36.9 years and a follow-up period of 34 months, were analyzed, revealing a malignancy occurrence rate of 1.05%, which is 10.45 times higher than the general population.
- By 30 years of diagnosis, the cumulative cancer risk for Indian individuals with CD was found to be 13.4%, covering various types of malignancies including bowel and extraintestinal cancers, but no cases of
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