Seven patients--six of whom died--underwent surgical repair of a ruptured abdominal aortic aneurysm and developed postoperative ischemic colitis. All patients were male, with a mean age of 62 years. Resection of the necrotic colon with a colostomy was necessary within the first postoperative week for the six patients who did not survive and on the 40th postoperative day for the patient who lived. The colon is vulnerable to ischemic necrosis after an aortic rupture because of tissue hypoperfusion and impaired mesenteric artery circulation due to preexistent occlusive disease. In high-risk patients, fiberoptic colonoscopy and examination of stool for occult blood, with immediate abdominal exploration, if necessary, are important in the early postoperative period. Symptoms may develop insidiously when tissue damage is limited to the mucosal layer, but delay in resecting the ischemic segment allows for the extension of necrosis, with perforation.
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http://dx.doi.org/10.1001/archsurg.1985.01390360034008 | DOI Listing |
Int J Cardiol Cardiovasc Risk Prev
March 2025
Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, 6997801, Israel.
Background: The relationship between inflammatory bowel diseases (IBD) and the risk of ischemic heart diseases (IHD) remains a subject of debate. In this study, we sought to investigate the association between IBD and long-term risk of IHD in a substantial cohort of IBD patients.
Methods: In this retrospective cohort study we utilized data from a state-mandated provider in Israel (Maccabi Healthcare Services).
Front Med (Lausanne)
January 2025
Institute of Gastroenterology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Ischemic colitis (IC) is a multifaceted condition that often manifests with nonspecific symptoms such as abdominal pain and bloody diarrhea, particularly in older adults with vascular risk factors. Diagnosis is supported by elevated levels of white blood cells, lactate, and C-reactive protein (CRP). Computed tomography (CT) imaging typically reveals wall thickening and fat stranding in watershed areas.
View Article and Find Full Text PDFPediatr Surg Int
December 2024
Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Introduction: This study investigates risk factors and surgical outcomes in pediatric patients with congenital heart defects (CHD) who develop ischemic colitis (IC). Previous research indicates a higher IC risk in very low birth weight neonates with CHD.
Methods: A retrospective analysis compared an IC-CHD group to a CHD-only group.
Ann Diagn Pathol
December 2024
Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:
Isolated ischemic necrosis of the cecum (INC) is an uncommon benign condition that occurs most often in elderly patients. The clinical presentation and radiographic findings often mimic acute appendicitis or malignancy. This study aimed to investigate the clinicopathologic features of mass-forming INC.
View Article and Find Full Text PDFJ Gastroenterol Hepatol
December 2024
Specialty Care Medical Affairs, Pfizer Japan Inc., Shibuya City, Tokyo, Japan.
Background And Aim: We conducted a retrospective study to identify incidence rates and potential risk factors of major adverse cardiac events (MACE) in Japanese patients with ulcerative colitis (UC), as existing data are scarce, inconsistent, and provide limited representation of the real-world situation of MACE in Japan.
Methods: We utilized administrative claims data, collected between January 2013 and December 2022, from Medical Data Vision, Japan. Patients (aged ≥ 20 years) diagnosed with UC within ± 1 month of the prescription date during the study period were included in the incident cohort.
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