AI Article Synopsis

Article Abstract

This report describes an entrapment syndrome of the superficial peroneal nerve terminal sensory branches. Two patients presented with numbness and tingling of the foot dorsum. These symptoms increased with activity such as walking, running, and squatting. The signs were 1) a decrease in sensation to light touch and pin prick on the foot dorsum over the cutaneous distribution of the nerve with sparing of the first web space; 2) a soft tissue bulge over the anterolateral aspect of the leg approximately 10 cm above the lateral malleolus; 3) a Tinel sign over the bulge; 4) an increase in the size of the bulge either with resisted ankle dorsiflexion or weight bearing; and 5) tenderness over the bulge or distally over the terminal sensory branches of the superficial peroneal nerve. Electrodiagnostic studies revealed an unrecordable evoked response or a prolonged distal latency of the terminal sensory branches of the superficial peroneal nerve. Treatment consisted of surgical decompression of the nerve at the bulge by fasciotomy. Patients responded with complete symptomatic relief. To provide accurate treatment, the diagnosis of entrapment syndrome of the superficial peroneal nerve terminal sensory branches must be differentiated from other causes of pain and numbness in the ankle area.

Download full-text PDF

Source

Publication Analysis

Top Keywords

terminal sensory
20
sensory branches
20
superficial peroneal
20
peroneal nerve
20
branches superficial
12
entrapment syndrome
12
syndrome superficial
8
nerve terminal
8
foot dorsum
8
nerve
7

Similar Publications

Background: Chronic neuropathic pain generally has a poor response to treatment with conventional drugs. Sympathectomy can alleviate neuropathic pain in some patients, suggesting that abnormal sympathetic-somatosensory signaling interactions might underlie some forms of neuropathic pain. The molecular mechanisms underlying sympathetic-somatosensory interactions in neuropathic pain remain obscure.

View Article and Find Full Text PDF

Deuterium (H) MRI is an emerging tool for noninvasive imaging. We explore the integration of H MRI with deuterated multifunctional nanopolymers for deuterated particle imaging (DPI). To this end, amine-terminated G5-polyamidoamine (PAMAM) dendrimers were labeled with deuterated acetyl surface groups, leading to highly H-loaded bioparticles, making them ideal for imaging studies.

View Article and Find Full Text PDF

Superior colliculus controls the activity of the substantia nigra pars compacta and ventral tegmental area in an asymmetrical manner.

J Neurosci

January 2025

Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Jagiellonian University, 9 Gronostajowa street, 30-387 Kraków, Poland.

Dopaminergic (DA) neurons of the substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) play a crucial role in controlling animals' orienting and approach behaviors toward relevant environmental stimuli. The ventral midbrain receives sensory input from the superior colliculus (SC), a tectal region processing information from contralateral receptive fields of various modalities. Given the significant influence of dopamine release imbalance in the left and right striatum on animals' movement direction, our study aimed to investigate the lateralization of the connection between the lateral SC and the midbrain DA system in male rats.

View Article and Find Full Text PDF

Differential neurogenic patterns underlie the formation of primary and secondary areas in the developing somatosensory cortex.

Cereb Cortex

January 2025

Department of Biology, Faculty of Education and Integrated Arts and Sciences, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, 162-8480, Tokyo, Japan.

Article Synopsis
  • The cerebral cortex has organized areas that are connected by axons, but how neurogenesis (the development of new neurons) is coordinated between these areas isn’t well understood.
  • The somatosensory cortex is important for processing touch and receives sensory information through the thalamus to its primary and secondary areas.
  • Our study found that neuron production in the secondary somatosensory cortex (S2) happens before the primary somatosensory cortex (S1) and ends sooner, with a decrease in upper-layer neurons in S2 due to a change at the surface layer, suggesting a specific mechanism that organizes the development of these cortical areas.
View Article and Find Full Text PDF

The refinement of neural circuits towards mature function is driven during development by patterned spontaneous calcium-dependent electrical activity. In the auditory system, this sensory-independent activity arises in the pre-hearing cochlea and regulates the survival and refinement of the auditory pathway. However, the origin and interplay of calcium signals during cochlear development is unknown in vivo.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!