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Consumption of a Branched-Chain Amino Acids-Containing Sports Beverage During 21 km of Running Reduces Dehydration, Lowers Muscle Damage, and Prevents a Decline in Lower Limb Strength.
Nutrients
November 2024
Department of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing 100084, China.
Objectives: The purpose of this study was to examine the acute effects of branched-chain amino acids (BCAAs)-containing electrolyte beverage (AE) on water-electrolyte balance, muscle damage, time to finish the final 5 km, and muscle strength compared to a standard commercially available carbohydrate-electrolyte sports beverage (CE), pure water (W), and no rehydration (N).
Methods: Fourteen trained male participants (20 ± 2 years old) completed four randomized 21 km running trials. The participants were instructed to consume their drink (150 mL W, 150 mL CE, or 150 mL AE) or no rehydration (N) at 5 km, 10 km, and 15 km.
[Association between early fluid balance and outcomes in patients receiving continuous renal replacement therapy for cardiac surgery-associated acute kidney injury].
Zhonghua Yi Xue Za Zhi
November 2024
Department of Nephrology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing210029, China.
To evaluate the association between fluid balance within 48 hours after initiating continuous renal replacement therapy (CRRT) and 90-day mortality of patients with cardiac surgery-associated acute kidney injury (CSA-AKI). Adult patients who received CRRT for CSA-AKI for more than 24 hours between January 2016 and December 2021 in the First Affiliated Hospital of Nanjing Medical University were prospectively included. Exposures were fluid input, fluid output, fluid balance and percentage of fluid overload change (defined as weight-standardized fluid input/output difference) within 48 hours after CRRT initiation.
View Article and Find Full Text PDFSex differences in the adrenal circadian clock: a role for BMAL1 in the regulation of urinary aldosterone excretion and renal electrolyte balance in mice.
Am J Physiol Renal Physiol
January 2025
Department of Physiology and Aging, University of Florida, Gainesville, Florida, United States.
Brain and muscle ARNT-Like 1 (BMAL1) is a circadian clock transcription factor that regulates physiological functions. Male adrenal-specific () KO mice displayed blunted serum corticosterone rhythms, altered blood pressure rhythm, and altered timing of eating, but there is a lack of knowledge in females. This study investigates the role of adrenal BMAL1 in renal electrolyte handling and urinary aldosterone levels in response to low salt in male and female mice.
View Article and Find Full Text PDFAdaptation mechanism of Phan Rang sheep to salinity in drinking water under tropical conditions.
Anim Sci J
October 2024
Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
The aims of this study were to determine adaptation mechanism of sheep to salinity in drinking water. A group of 10 male sheep were used in a 6-week of experiment, with 1 week for pre-treatment period (Week 1), 4 weeks for during treatment period (Week 2 to Week 5), and 1 week for posttreatment period (Week 6). During the pre- and posttreatment periods, sheep consumed with fresh water.
View Article and Find Full Text PDFWater and sodium conservation response induced by SGLT2 inhibitor ipragliflozin in Dahl salt-sensitive hypertensive rats.
Hypertens Res
November 2024
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Sodium-glucose cotransporter 2 (SGLT2) inhibitors increase urine volume with glucosuria and natriuresis. We recently reported that osmotic diuresis by the SGLT2 inhibitor ipragliflozin induces fluid homeostatic action via the stimulation of fluid intake and vasopressin-induced water reabsorption in euvolemic rats. However, the effects of SGLT2 inhibitors on these parameters in hypervolemic animals remain unclear.
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