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- Lumbar degenerative spondylolisthesis (LDS) is a condition involving spinal instability due to intervertebral disc degeneration and facet joint changes, leading to pain and potential surgery, but its causes are not well understood.
- This study examined the relationship between gut microbiome dysbiosis (an imbalance of gut bacteria) and spine health in symptomatic patients with and without LDS by analyzing fecal samples.
- Findings indicated that patients with LDS showed more severe disc degeneration, distinct gut microbiome structures, and a higher ratio of pro-inflammatory bacteria compared to those without LDS, suggesting a possible link between gut health and spinal conditions.
The search for systemic biomarkers for monitoring degenerative lumbar spinal disorders.
Osteoarthr Cartil Open
December 2022
Deparment of Morphological Sciences, Adelson School of Medicine, Ariel University, Ariel, Israel.
Objectives: In our previous study, we reported that low back pain (LBP) severity and disability significantly correlate with body composition and several blood biochemical factors. Herein, we tested the hypothesis that these covariates are associated with anatomical deformations of the lumbar spine, in particular, radiographic facet joint osteoarthritis (FJOA) and lumbar disc degeneration (LDD) features important contributors to LBP.
Methods: CT and MRI images of the lumbar spine were obtained from 200 individuals suffering from LBP-sciatica.
EPIDURAL INJECTIONS IN THE TREATMENT OF RADICULAR SYNDROME AND CHRONIC LOWER BACK PAIN IN DEGENERATIVE-DYSTROPHIC SPINE DAMAGE.
Georgian Med News
October 2022
State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department, Department of Miniinvasive Surgery Kyiv, Ukraine.
Purpose of the study - to investigate the methodology and effectiveness of epidural steroid injection for radicular syndrome and lower back pain caused by degenerative-dystrophic spine damage. Research methods: bibliosemantic, comparative, systemic approach. The analysis of early and long-term results of treatment of patients with degenerative-dystrophic spine damage using epidural steroid injections by various authors and the author's own experience was carried out.
View Article and Find Full Text PDFRespective Correction Rates of Lateral Lumbar Interbody Fusion and Percutaneous Pedicle Screw Fixation for Lumbar Degenerative Spondylolisthesis.
Medicina (Kaunas)
January 2022
Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare (IUHW), Chiba 286-8520, Japan.
There are few reports describing the radiographic correction of vertebral slippage in lateral interbody fusion and percutaneous pedicle screw fixation for lumbar degenerative spondylolisthesis. [Objectives] We evaluated the intraoperative surgical correction obtained by lateral interbody fusion and percutaneous pedicle screw procedures. Fifty patients were included in this study.
View Article and Find Full Text PDFAnalysis of Patient-reported Outcomes Measures Used in Lumbar Fusion Surgery Research for Degenerative Spondylolisthesis.
Clin Spine Surg
July 2022
Center for Spine Health, Cleveland Clinic, Cleveland, OH.
Study Design: Meta-analyses.
Objective: This study aims to document the most common Patient-reported Outcome Measures (PROMs) used to assess lumbar fusion surgery outcomes and provide an estimate of the average improvement following surgical treatment.
Summary Of Background Data: As health care institutions place more emphasis on quality of care, accurately quantifying patient perceptions has become a valued tool in measuring outcomes.
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