The results of a 7-year prospective follow-up of a representative sample of men aged 45-49 years living in Kaunas, who were initially examined within the framework of the Kaunas-Rotterdam Intervention Study, are presented. The relationship was investigated between systolic and diastolic hypertension, hypercholesterolaemia, smoking impaired glucose tolerance on the one hand, and mortality (total and from ischaemic heart disease) on the other hand. The main cause of death in the studied series were cardiovascular diseases (38.7%); of these, in 62% of cases ischaemic heart disease. Among subjects who had been found healthy at screening, the most unfavourable prognosis as regards mortality from ischaemic heart disease, had men with hypertension.
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