The results of an IAEA/WHO 14-year survey on the precision of irradiation at a preset dose (2 Gy) in radiotherapy departments in different countries have shown that nearly in 40% of cases deviations from a preset dose exceeded the tolerant rate (+/- 5%). A conclusion has been made of the necessity to develop a program of quality guarantee in radiotherapy at national and international levels.
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Quant Imaging Med Surg
January 2025
Department of Imaging Medicine and Nuclear Medicine, Shandong Second Medical University, Weifang, China.
Background: Rapid kilovolt (kV)-switching dual-energy computed tomography (DECT) has been increasingly applied to the measurement of lumbar spine bone mineral density (BMD) in humans and animal models. The objective of this study was to investigate the optimal parameters for the measurement of vertebral BMD. The BMD of the spinal model was measured by means of DECT in combination with different noise index (NI) and preset adaptive statistical iterative reconstruction Veo (ASiR-V) levels.
View Article and Find Full Text PDFBMJ Open
December 2024
Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK
Introduction: Cortisol is an essential stress hormone and failure of its production, known as adrenal insufficiency (AI), is associated with significant mortality due to adrenal crisis. The Short Synacthen Test (SST) is the current diagnostic test of choice for AI, but it is both invasive and resource intensive. Globally, there is an unmet need for a non-invasive, cost-effective test.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
The management of type 1 diabetes in pregnancy with new technologies is challenging. Sometimes the complexity of new-generation systems such as "continuous subcutaneous insulin infusion, CSII" and patient or provider preference do not allow their use, so women with type 1 diabetes in pregnancy continue to be treated with subcutaneous multiple-injection insulin therapy using pens. Smart insulin pens are new tools that allow for data collection on insulin dose and time of administration and have additional connectivity features.
View Article and Find Full Text PDFTransplant Proc
November 2024
Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Introduction: Hypercoagulability-related graft thrombosis is the leading cause of graft failure after simultaneous pancreas-kidney transplantation (SPK). Addressing this issue is crucial to improve the outcomes of SPK recipients. Thromboelastography (TEG) has been used to assess the coagulation profiles of SPK recipients.
View Article and Find Full Text PDFBackground And Objective: Delivering radiotherapy to the bladder is challenging as it is a mobile, deformable structure. Dose-escalated adaptive image-guided radiotherapy could improve outcomes. RAIDER aimed to demonstrate the safety of such a schedule.
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