DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1049455 | PMC |
| http://dx.doi.org/10.1136/jmg.22.4.305 | DOI Listing |
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