The histopathological lesions remaining after microsurgical tubal reanastomosis were investigated quantitatively by light microscopy and qualitatively by transmission and scanning electron microscopy. In 23 rabbit oviducts, the influence of the suture material poly-p-dioxanon and polyglactin-910 and post-operative time interval (6 and 12-15 weeks) was evaluated and compared with non-anastomosed contralateral oviducts as well as with those of unoperated controls. Except in the controls, partial deciliation, pathological kinocilia structure, microvilli and cytoplasmic blebs were found in all tissues, demonstrating an almost complete endosalpingeal restoration. A statistically significant increase of the muscular thickness was observed on the operated and unoperated sides and was due to fibrosis and expressed by cell/stroma ratio. Subepithelial microgland-like structures also appeared on both sides. As neither the kind of suture material nor time intervals led to differences in tissue reaction and, moreover, as similar alterations were found in the non-anastomosed oviducts, the lesions are presumed to be mainly the response to laparotomy.
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