A new simian embryo cell line has been established from a Cercopithecus male whole embryo. The resultant predominant fibroblast-like cell population has been frozen in convenient quantities and characterized for use in biological research as well as in theoretical and practical virological purposes. The cell line was designated ICCe-1 (Institute Cantacuzino Cercopithecus embryo-1).
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Trophoblast stem cells (TSCs) are a proliferative multipotent population derived from the trophectoderm of the blastocyst, which will give rise to all the functional cell types of the trophoblast compartment of the placenta. The isolation and culture of TSCs in vitro represent a robust model to study mechanisms of trophoblast differentiation into mature cells both in successful and diseased pregnancy. Despite the highly conserved functions of the placenta, there is extreme variability in placental morphology, fetal-maternal interface, and development among eutherian mammals.
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