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Changes in epinephrine, norepinephrine and dopamine levels in different brain nuclei of the August rats were studied after 6.5-hr immobilization. The linkage between the BP dynamics under emotional stress and changes of catecholamines content was observed in epinephrinsynthetizing area A1, norepinephrinsynthetizing area A6 (locus Coeruleus) and dopaminsynthetizing area A9 (substantia nigra). Sharp increase of the BP in the August rats was related to obvious decrease of epinephrine content in A1, norepinephrine in locus coeruleus and dopamine in substantia nigra. The data obtained suggest that deficit of the catecholamines due to the metabolic changes during emotional stress may result in distutbances of the cardiovascular functions control in the August rats.
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