The paper is devoted to analysis of results of the investigation of the motor-evacuatory function of the stomach at different terms after truncal vagotomy with antrumectomy in patients with complicated duodenal ulcers. Postvagotomy gastrostasis was shown to be twice more frequent after antral resection with anastomosis by Billroth-I than by billroth-II. Truncal vagotomy with antrumectomy is not recommended for patients with duodenal ulcers complicated by decompensated stenosis. Gastric resection is thought to be the operation of choice in such cases.
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Brain Behav Immun
November 2024
Chiba University Center for Forensic Mental Health, Chiba, Japan. Electronic address:
The vagus nerve is a crucial component of the parasympathetic nervous system, facilitating communication between the brain and various organs, including the ears, heart, lungs, pancreas, spleen, and gastrointestinal tract. The caudal nucleus of the solitary tract in the brainstem is the initial site regulated by the vagus nerve in brain-body communication, including the interactions with immune system. Increasing evidence suggests that the gut-brain axis, via the vagus nerve, may play a role in the development and progression of psychiatric, neurologic, and inflammation-related disorders.
View Article and Find Full Text PDFNeuron
November 2024
Faculty of Life and Health Sciences, Shenzhen University of Advanced Technology (SUAT), Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China. Electronic address:
medRxiv
April 2024
Institute of Veterinary Pharmacology and Toxicology, University of Zurich-Vetsuisse, Switzerland.
Background And Objectives: Emerging preclinical evidence suggests that vagal signals contribute to the development of schizophrenia-related abnormalities in brain and behavior. Whether vagal communication in general, and its impairment in particular, is a risk factor for schizophrenia in humans remains, however, unclear. Vagotomy, the surgical lesion of the vagus nerve, was routinely performed as a treatment for peptic ulcer before modern treatment options were available.
View Article and Find Full Text PDFACG Case Rep J
January 2024
Davis Medical Center, University of California, Sacramento, CA.
is a known cause of peptic ulcers, but it has not been reported to cause strictures in children. We present the case of a previously healthy 12-year-old boy with sudden onset of abdominal pain and vomiting, positive stool antigen testing, and esophagogastroduodenoscopy revealing a gastroduodenal stricture causing gastric outlet obstruction. Because of medically refractory disease, he ultimately required laparoscopic truncal vagotomy with open pyloroplasty.
View Article and Find Full Text PDFBMB Rep
March 2024
Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul 03080, Korea.
The stomach has emerged as a crucial endocrine organ in the regulation of feeding since the discovery of ghrelin. Gut-derived hormones, such as ghrelin and cholecystokinin, can act through the vagus nerve. We previously reported the satiety effect of hypothalamic clusterin, but the impact of peripheral clusterin remains unknown.
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