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Left Ventricular Hypertrabeculation (LVHT) in Athletes: A Negligible Finding?

Medicina (Kaunas)

December 2024

Clinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03225 Vilnius, Lithuania.

Left ventricular hypertrabeculation (LVHT) used to be a rare phenotypic trait. With advances in diagnostic imaging techniques, LVHT is being recognised in an increasing number of people. The scientific data show the possibility of the overdiagnosis of this cardiomyopathy in a population of people who have very high levels of physical activity.

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Background: High-intensity endurance training induces specific cardiac adaptations, often observed through electrocardiographic (ECG) changes. This study investigated the prevalence of ECG abnormalities in national-level Australian triathletes compared to sedentary controls.

Methods: A cross-sectional observational study was conducted involving 22 triathletes and 7 sedentary controls.

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Cardiac adaptations in young triathletes: a 9-month longitudinal study during the peak height velocity period.

Eur J Appl Physiol

January 2025

Laboratoire de Pharm-Ecologie Cardiovasculaire (EA 4278), Université d'Avignon, 33 Rue Louis Pasteur, 84000, Avignon, France.

Purpose: The present study examined the influence of endurance training on the morphological and functional heart adaptations in young athletes throughout a longitudinal 9-month follow-up period during the adolescent peak height velocity (PHV).

Methods: Thirty-six 13- to 15-year-old males (twenty-three triathletes and thirteen untrained peers) were evaluated before and after a 9-month period during PHV. Maximal oxygen uptake ( ) and power at were assessed during incremental cycling test.

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Striking Cardioprotective Effects of an Adiponectin Receptor Agonist in an Aged Mouse Model of Duchenne Muscular Dystrophy.

Antioxidants (Basel)

December 2024

Pole of Cardiovascular Research, Institute of Experimental and Clinical Research (IREC), Université Catholique de Louvain (UCLouvain), Avenue Hippocrate 55, 1200 Brussels, Belgium.

Adiponectin (ApN) is a hormone with potent effects on various tissues. We previously demonstrated its ability to counteract Duchenne muscular dystrophy (DMD), a severe muscle disorder. However, its therapeutic use is limited.

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Background: Long-term endurance training is associated with structural, functional, and biochemical markers of cardiac dysfunction in highly trained athletes. Many studies have focused on structural changes in the right ventricle (RV) and few have examined functional adaptation of the right ventricle. This meta-analysis aims to compare the changes in right ventricular systolic function between endurance athletes and controls before and after exercise using speckle tracking echocardiography (STE).

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