A clinical review is presented of patients with disabling rheumatoid arthritis at the base of the thumb treated by resection of the trapezium or by implant arthroplasty. Both methods resulted in good relief of pain, and the patients experienced better hand function. There were no great differences in results between the two methods.

Download full-text PDF

Source
http://dx.doi.org/10.1016/0266-7681(85)90015-4DOI Listing

Publication Analysis

Top Keywords

rheumatoid arthritis
8
arthritis base
8
base thumb
8
thumb treated
8
implant arthroplasty
8
treated trapezium
4
trapezium resection
4
resection implant
4
arthroplasty clinical
4
clinical review
4

Similar Publications

Introduction: Folate receptors (FR) have been considered a convenient target for different radiopharmaceuticals in recent years. Multifarious Ga-labeled folate conjugates have been proposed as promising agents for the PET imaging of FR-overexpressing malignant neoplasms. In addition, radiolabeled folate-based conjugates can be effective for imaging non-tumor pathological foci characterized by a pronounced cluster of activated macrophages.

View Article and Find Full Text PDF

One key determinant of HIV-1 latency reversal is the activation of the viral long terminal repeat (LTR) by cellular transcription factors such as NF-κB and AP-1. Interestingly, the activity of these two transcription factors can be modulated by glucocorticoid receptors (GRs). Furthermore, the HIV-1 genome contains multiple binding sites for GRs.

View Article and Find Full Text PDF

A new twist on superantigen-activated autoimmune disease.

J Clin Invest

January 2025

Division of Rheumatology, Center of Excellence for Intestinal and Immunology Research, University of Alberta, Edmonton, Alberta, Canada.

Superantigen-induced (Sag-induced) autoimmunity has been proposed as a mechanism for many human disorders, without a clear understanding of the potential triggers. In this issue of the JCI, McCarthy and colleagues used the SKG mouse model of rheumatoid arthritis to characterize the role of Sag activity in inflammatory arthritis by profiling arthritogenic naive CD4+ T cells. Within the diseased joints, they found a marked enrichment of T cell receptor-variable β (TCR-Vβ) subsets that were reactive to the endogenously encoded mouse mammary tumor virus (MMTV) Sag.

View Article and Find Full Text PDF

A wide variety of degenerative, inflammatory and infective arthropathies with overlapping clinical features can involve the knee joint. Due to its excellent soft tissue contrast resolution and multiplanar capability, magnetic resonance imaging (MRI) plays a significant role in early and accurate diagnosis of various arthropathies. In this article, we have provided a brief review of MRI features of various arthropathies involving the knee joint.

View Article and Find Full Text PDF

Diabetes mellitus type 2 (DM2) is a prevalent metabolic condition affecting over 500 million people globally and associated with serious comorbidities, including various rheumatologic conditions. Some studies have reported a significant association between rheumatological conditions and DM2. However, the global burden of rheumatological conditions among people with DM2 remains unknown.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!