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Ocular Manifestations of IBD: Pathophysiology, Epidemiology, and Iatrogenic Associations of Emerging Treatment Strategies.
Biomedicines
December 2024
Department of Gastroenterology, The Royal Wolverhampton NHS Trust, Wolverhampton WV10 0QP, UK.
Inflammatory bowel disease (IBD) is a complex, multisystemic disease and is associated with ocular pathology in 4-12% of patients. In general, ocular disease affects Crohn's patients more frequently than those with ulcerative colitis. Episcleritis and uveitis are the most common presentations, with episcleritis often correlating with IBD flares, whereas uveitis presents independently of IBD activity and, in some cases, may even alert clinicians to a new diagnosis of IBD.
View Article and Find Full Text PDFAmeboma, a rare cause of intestinal obstruction in bariatric surgery patients: a case report.
J Surg Case Rep
December 2024
Bariatric Surgery, Obesity Goodbye Center, Tijuana 22000, Mexico.
Article Synopsis
- - Ameboma is a rare complication from invasive amebiasis caused by a specific intestinal protozoan, leading to tumor-like inflammatory masses in the lower right abdomen.
- - Symptoms can vary but often include intestinal obstruction and gastrointestinal bleeding, and while imaging techniques like CT and ultrasound can reveal colonic masses, biopsy remains the most reliable way to diagnose ameboma.
- - Treatment generally involves targeting the protozoan causing the infection, with surgery being necessary for severe cases like intestinal obstruction or other serious complications.
Computed Tomography and Magnetic Resonance Enterography: From Protocols to Diagnosis.
Diagnostics (Basel)
November 2024
Department of Diagnostic Radiology, IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, Italy.
Article Synopsis
- - Both Magnetic Resonance Enterography (MRE) and Computed Tomography Enterography (CTE) are important imaging techniques used for diagnosing and treating inflammatory bowel disease (IBD), with CTE being favored in urgent situations like suspected complications.
- - CTE provides rapid and precise imaging but involves exposure to ionizing radiation, while MRE avoids radiation and excels in evaluating the small intestine and perianal disease, making it ideal for patients requiring frequent monitoring or those who are pregnant.
- - The review highlights the strengths and weaknesses of both imaging methods, aiming to inform about their technical aspects, benefits, limitations, and the specific findings they can reveal regarding IBD.
18F-FDG-PET and other imaging modalities in the diagnosis and management of inflammatory bowel disease.
Am J Nucl Med Mol Imaging
October 2024
Department of Radiology, University of Pennsylvania Philadelphia, Pennsylvania, The United States.
Inflammatory bowel disease (IBD), which encompasses ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal (GI) tract that presents complex diagnostic and management challenges. Early detection and treatment of IBD is paramount, as IBD can present with serious complications, including bowel perforation, arthritis, and colorectal cancer. Most forms of diagnosis and therapeutic management, like ileocolonoscopy and upper endoscopy are highly invasive and require extensive preparation at great discomfort to patients.
View Article and Find Full Text PDFVedolizumab to prevent postoperative recurrence of Crohn's disease (REPREVIO): a multicentre, double-blind, randomised, placebo-controlled trial.
Lancet Gastroenterol Hepatol
January 2025
Hospital du Haut-Leveque, Pessac, France.
Background: Approximately half of patients with Crohn's disease require ileocolonic resection. Of these, 50% will subsequently have endoscopic disease recurrence within 1 year. We aimed to evaluate the efficacy and safety of vedolizumab to prevent postoperative recurrence of Crohn's disease.
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