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Mortality variability and differentials by age and causes of death in rural South Africa, 1994-2018.
BMJ Glob Health
April 2024
School of Demography, The Australian National University, Acton, Australian Capital Territory, Australia.
Introduction: Understanding mortality variability by age and cause is critical to identifying intervention and prevention actions to support disadvantaged populations. We assessed mortality changes in two rural South African populations over 25 years covering pre-AIDS and peak AIDS epidemic and subsequent antiretroviral therapy (ART) availability.
Methods: Using population surveillance data from the Agincourt Health and Socio-Demographic Surveillance System (AHDSS; 1994-2018) and Africa Health Research Institute (AHRI; 2000-2018) for 5-year periods, we calculated life expectancy from birth to age 85, mortality age distributions and variation, and life-years lost (LYL) decomposed into four cause-of-death groups.
Background: There are few data about disease progression and response to antiretroviral therapy (ART) in vertically HIV-infected infants in the era of effective therapy.
Design: Cohort study.
Methods: We examined progression to acquired immunodeficiency syndrome (AIDS) and death over calendar time for infants reported to the National Study of HIV in Pregnancy and Childhood in the United Kingdom/Ireland.
[Intestinal parasitic diseases in HIV-infected patients in Uzbekistan].
Med Parazitol (Mosk)
November 2005
Intestinal parasitic diseases were diagnosed in 100 HIV-infected patients at different stages of disease (its asymptomatic form, persistent generalized lymphoadenopathy, pre-AIDS, and AIDS) (Group 1), 100 Tashkent residents (Group 2), and 349 patients with gastrointestinal diseases, allergic dermatoses, and skin depigmentation foci (Group 3). The HIV-infected patients were found to have virtually all parasites, such as Giardia lamblia, Cryptosporidium parvum, Chilomastix mesnili, Entamoeba coli, Iodamoeba butschlii, Entamoeba histolytica/dispar, Endolimax nana, Blastocystis hominis, Enlerobius vermicularis, Ascaris lumbricoides, Hymenolepis nana, detectable in the population of Tashkent. The highest infestation with intestinal protozoa, including nonpathogenic amoebas and helmninths, was found in Groups 1 and 3.
View Article and Find Full Text PDFClinical and Immunological Features of HIV-Infection in Children Aged 3-5 and 6-14 Years.
Russ J Immunol
April 1998
Rostov-on-Don State Medical University, Rostov-on-Don, Russia.
Ninety-five HIV-infected children aged 3-5 and 6-14 years were examined. Clinical picture matched primary symptoms of stage IIV (phase of generalized lymphadenopathy by Pokrovsky V.I.
View Article and Find Full Text PDFDisseminated cutaneous histoplasmosis in patients infected with human immunodeficiency virus.
J Cutan Pathol
April 2002
Department of Anatomical Pathology, Nelson R. Mandela School of Medicine, Faculty of Health Sciences, University of Natal, Durban, South Africa.
Background: In the pre-AIDS era disseminated histoplasmosis was rare and the cutaneous manifestations thereof were reported infrequently. A range of unusual clinical manifestations of disseminated cutaneous histoplasmosis (DCH) in AIDS patients has been documented, but the cutaneous histopathological descriptions are short and incomplete. In addition, the histopathological spectrum of AIDS-associated DCH is poorly recognized.
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